Cell Biology Antibodies 13
Anti-PLEK2 Antibody (CAB17682)
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- SKU:
- CAB17682
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PLEK2 Antibody |
| Antibody SKU: | CAB17682 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PLEK2 (NP_057529.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse stomach, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PLEK2 (NP_057529.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEDG VLKE GFLV KRGH IVHN WKAR WFIL RQNT LVYY KLEG GRRV TPPK GRIL LDGC TITC PCLE YENR PLLI KLKT QTST EYFL EACS REER DAWA FEIT GAIH AGQP GKVQ QLHS LRNS FKLP PHIS LHRI VDKM HDSN TGIR SSPN MEQG STYK KTFL GSSL VDWL ISNS FTAS RLEA VTLA SMLM EENF LRPV GVRS MGAI RSGD LAEQ FLDD STAL YTFA ESYK KKIS PKEE ISLS TVEL SGTV VK |
| Gene ID: | 26499 |
| Uniprot: | Q9NYT0 |
| Cellular Location: | |
| Calculated MW: | 39kDa |
| Observed MW: | 40kDa |
 | Western blot - PLEK2 Polyclonal Antibody (CAB17682) |
| Synonyms: | PLEK2 |
| Background: | The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015] |
| UniProt Protein Function: | PLEK2: May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 14q23.3-q24.1 Cellular Component: cytoplasm; cytoskeleton Molecular Function:phosphatidylinositol-3,4-bisphosphate binding Biological Process: actin cytoskeleton organization; positive regulation of cell projection organization |
| NCBI Summary: | The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q9NYT0 |
| NCBI GenInfo Identifier: | 7706643 |
| NCBI Gene ID: | 26499 |
| NCBI Accession: | NP_057529.1 |
| UniProt Secondary Accession: | Q9NYT0,Q96JT0, |
| UniProt Related Accession: | Q9NYT0 |
| Molecular Weight: | 39,971 Da |
| NCBI Full Name: | pleckstrin-2 |
| NCBI Synonym Full Names: | pleckstrin 2 |
| NCBI Official Symbol: | PLEK2 |
| NCBI Protein Information: | pleckstrin-2 |
| UniProt Protein Name: | Pleckstrin-2 |
| Protein Family: | Pleckstrin |
| UniProt Gene Name: | PLEK2 |
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