Cell Biology Antibodies 18
Anti-PLD3 Antibody (CAB18438)
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- SKU:
- CAB18438
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PLD3 Antibody |
| Antibody SKU: | CAB18438 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PLD3. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse testis, Mouse lung, Mouse brain |
| Immunogen: | Recombinant protein of human PLD3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23646 |
| Uniprot: | Q8IV08 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 55kDa |
 | Western blot - PLD3 Rabbit pAb (CAB18438) |
| Synonyms: | AD19, HU-K4, HUK4, PLD3 |
| Background: |
| UniProt Protein Function: | PLD3: Belongs to the phospholipase D family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Phospholipase; EC 3.1.4.4; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: endoplasmic reticulum membrane; integral to membrane Molecular Function:phospholipase D activity; protein binding Biological Process: glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylglycerol biosynthetic process; phospholipid metabolic process Disease: Alzheimer Disease 19 |
| NCBI Summary: | This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014] |
| UniProt Code: | Q8IV08 |
| NCBI GenInfo Identifier: | 605052028 |
| NCBI Gene ID: | 23646 |
| NCBI Accession: | NP_001278240.1 |
| UniProt Secondary Accession: | Q8IV08,Q92853, Q9BW87, |
| UniProt Related Accession: | Q8IV08 |
| Molecular Weight: | 54,705 Da |
| NCBI Full Name: | phospholipase D3 |
| NCBI Synonym Full Names: | phospholipase D family member 3 |
| NCBI Official Symbol: | PLD3 |
| NCBI Official Synonym Symbols: | AD19; HUK4; HU-K4 |
| NCBI Protein Information: | phospholipase D3 |
| UniProt Protein Name: | Phospholipase D3 |
| UniProt Synonym Protein Names: | Choline phosphatase 3; HindIII K4L homolog; Hu-K4; Phosphatidylcholine-hydrolyzing phospholipase D3 |
| Protein Family: | Phospholipase |
| UniProt Gene Name: | PLD3 |
| UniProt Entry Name: | PLD3_HUMAN |
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