Metabolism Antibodies 1

Anti-PLD2 Antibody (CAB10192)

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SKU:
CAB10192
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-PLD2 Antibody
Antibody SKU:CAB10192
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PLD2 (NP_002654.3).
Application:WB
Recommended Dilution:WB 1:1000 - 1:3000
Reactivity:Human, Mouse, Rat
Positive Samples:B-cell, HeLa, U-87MG, BT-474, A375
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PLD2 (NP_002654.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MTAT PESL FPTG DELD SSQL QMES DEVD TLKE GEDP ADRM HPFL AIYE LQSL KVHP LVFA PGVP VTAQ VVGT ERYT SGSK VGTC TLYS VRLT HGDF SWTT KKKY RHFQ ELHR DLLR HKVL MSLL PLAR FAVA YSPA RDAG NREM PSLP RAGP EGST RHAA SKQK YLEN YLNR LLTM SFYR
Gene ID:5338
Uniprot:O14939
Cellular Location:Membrane, Peripheral membrane protein
Calculated MW:38kDa/104kDa/105kDa
Observed MW:110kDa
Synonyms:PLD2, PLD1C
Background:The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4, 5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:May have a role in signal-induced cytoskeletal regulation and/or endocytosis.
NCBI Summary:The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
UniProt Code:O14939
NCBI GenInfo Identifier:13124441
NCBI Gene ID:5338
NCBI Accession:O14939.2
UniProt Secondary Accession:O14939,O43540, O43579, O43580, Q6PGR0, Q96BY3, I3L2C9
UniProt Related Accession:O14939
Molecular Weight:104,657 Da
NCBI Full Name:Phospholipase D2
NCBI Synonym Full Names:phospholipase D2
NCBI Official Symbol:PLD2  
NCBI Official Synonym Symbols:PLD1C  
NCBI Protein Information:phospholipase D2
UniProt Protein Name:Phospholipase D2
UniProt Synonym Protein Names:Choline phosphatase 2; PLD1C; Phosphatidylcholine-hydrolyzing phospholipase D2
Protein Family:Phospholipase
UniProt Gene Name:PLD2  
Anti-PLD2 Antibody (CAB10192)Western blot analysis of extracts of various cell lines, using PLD2 antibody (CAB10192) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
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