Cell Biology Antibodies 1

Anti-PLA2R1 Antibody (CAB10068)

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SKU:
CAB10068
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PLA2R1 Antibody
Antibody SKU:CAB10068
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1 (NP_031392.3).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, SH-SY5Y, Mouse liver, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1 (NP_031392.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GASW WIGL QEER ANDE FRWR DGTP VIYQ NWDT GRER TVNN QSQR CGFI SSIT GLWG SEEC SVSM PSIC KRKK VWLI EKKK DTPK QHGT CPKG WLYF NYKC LLLN IPKD PSSW KNWT HAQH FCAE EGGT LVAI ESEV EQAF ITMN LFGQ TTSV WIGL QNDD YETW LNGK PVVY SNWS PFDI INIP SHNT TEVQ KHIP LCAL LSSN PNFH FTGK WYFE DCGK EGYG FVCE KMQD TSGH GVNT SDMY PMPN TLEY GNRT YKII N
Gene ID:22925
Uniprot:Q13018
Cellular Location:Cell membrane, Secreted, Single-pass type I membrane protein
Calculated MW:152kDa/168kDa
Observed MW:169kDa
Synonyms:CLEC13C, PLA2-R, PLA2G1R, PLA2IR, PLA2R, PLA2R1
Background:This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Summary:This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
UniProt Code:Q13018
NCBI GenInfo Identifier:691753
NCBI Gene ID:22925
NCBI Accession:
UniProt Related Accession:Q13018
Molecular Weight:
NCBI Full Name:phospholipase A2 receptor, partial
NCBI Synonym Full Names:phospholipase A2 receptor 1
NCBI Official Symbol:PLA2R1  
NCBI Official Synonym Symbols:PLA2R; PLA2-R; PLA2IR; CLEC13C; PLA2G1R  
NCBI Protein Information:secretory phospholipase A2 receptor
UniProt Protein Name:
UniProt Gene Name:
Anti-PLA2R1 Antibody (CAB10068)Western blot analysis of extracts of various cell lines, using PLA2R1 antibody (CAB10068) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-PLA2R1 Antibody (CAB10068)Immunohistochemistry of paraffin-embedded rat liver using PLA2R1 antibody (CAB10068) at dilution of 1:100 (40x lens).
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