Cell Biology Antibodies 16

Anti-PLA2G6 Antibody (CAB14808)

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SKU:
CAB14808
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PLA2G6 Antibody
Antibody SKU:CAB14808
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 350-450 of mouse PLA2G6 (NP_001185952.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 350-450 of mouse PLA2G6 (NP_001185952.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GNTP LHLA MSKD NMEM VKAL IVFG AEVD TPND FGET PALI ASKI SKLI TRKA LLTL LKTV GADH HFPI IQGV STEQ GSAA ATHP LFSL DRTQ PPAI SLNN L
Gene ID:53357
Uniprot:
Cellular Location:Cytoplasm, Membrane, Peripheral membrane protein
Calculated MW:83kDa/89kDa
Observed MW:Refer to figures
Synonyms:PLA2G6, CaI-PLA2, GVI, INAD1, IPLA2-VIA, NBIA2, NBIA2A, NBIA2B, PARK14, PLA2, PNPLA9, iPLA2, iPLA2beta
Background:The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.
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