Metabolism Antibodies 2
Anti-PLA2G2D Antibody (CAB7165)
(No reviews yet)
Write a Review
- SKU:
- CAB7165
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-PLA2G2D Antibody |
| Antibody SKU: | CAB7165 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-145 of human PLA2G2D (NP_036532.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
| Reactivity: | Human, Rat |
| Positive Samples: | Rat lung, Rat spinal cord |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-145 of human PLA2G2D (NP_036532.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GILN LNKM VKQV TGKM PILS YWPY GCHC GLGG RGQP KDAT DWCC QTHD CCYD HLKT QGCS IYKD YYRY NFSQ GNIH CSDK GSWC EQQL CACD KEVA FCLK RNLD TYQK RLRF YWRP HCRG QTPG C |
| Gene ID: | 26279 |
| Uniprot: | Q9UNK4 |
| Cellular Location: | Secreted |
| Calculated MW: | 16kDa |
| Observed MW: | 17kDa |
| Synonyms: | PLA2G2D, PLA2IID, SPLASH, sPLA2-IID, sPLA2S |
| Background: | This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | PLA2G2D: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. Belongs to the phospholipase A2 family. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - linoleic acid; Lipid Metabolism - ether lipid; Phospholipase; Lipid Metabolism - arachidonic acid; Secreted; Secreted, signal peptide; Lipid Metabolism - glycerophospholipid; EC 3.1.1.4 Chromosomal Location of Human Ortholog: 1p36.12 Cellular Component: extracellular region Molecular Function:phospholipase A2 activity; calcium ion binding Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; inflammatory response; lipid catabolic process |
| NCBI Summary: | This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q9UNK4 |
| NCBI GenInfo Identifier: | 20139286 |
| NCBI Gene ID: | 26279 |
| NCBI Accession: | Q9UNK4.2 |
| UniProt Secondary Accession: | Q9UNK4,Q9UK01, A8K2Z1, B1AEL9, |
| UniProt Related Accession: | Q9UNK4 |
| Molecular Weight: | 145 |
| NCBI Full Name: | Group IID secretory phospholipase A2 |
| NCBI Synonym Full Names: | phospholipase A2, group IID |
| NCBI Official Symbol: | PLA2G2D |
| NCBI Official Synonym Symbols: | SPLASH; sPLA2S; PLA2IID; sPLA2-IID |
| NCBI Protein Information: | group IID secretory phospholipase A2; GIID sPLA2; secretory phospholipase A2s; phosphatidylcholine 2-acylhydrolase 2D; secretory-type PLA, stroma-associated homolog |
| UniProt Protein Name: | Group IID secretory phospholipase A2 |
| UniProt Synonym Protein Names: | PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homolog |
| Protein Family: | Group IID secretory phospholipase |
| UniProt Gene Name: | PLA2G2D |
| UniProt Entry Name: | PA2GD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PLA2G2D antibody (CAB7165) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of U2OS cells using PLA2G2D antibody (CAB7165). Blue: DAPI for nuclear staining. |
View AllClose
Related Products
Human PLA2G2D Recombinant Protein (RPPB2122)
Enzymes Recombinant Proteins
system_update_altDatasheetsystem_update_altMSDS
Human PLA2G2D Recombinant Protein (RPES2656)
Metabolism Recombinant Proteins
system_update_altDatasheetHuman PLA2G2D Recombinant Protein The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48)
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
