Immunology Antibodies 2

Anti-PLA2G16 Antibody (CAB16018)

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SKU:
CAB16018
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-PLA2G16 Antibody
Antibody SKU:CAB16018
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 68-162 of human PLA2G16 (NP_009000.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HepG2, HT-29
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 68-162 of human PLA2G16 (NP_009000.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VAGS DKYQ VNNK HDDK YSPL PCSK IIQR AEEL VGQE VLYK LTSE NCEH FVNE LRYG VARS DQVR DVII AASV AGMG LAAM SLIG VMFS RNKR QKQ
Gene ID:11145
Uniprot:P53816
Cellular Location:
Calculated MW:18kDa
Observed MW:18kDa
Synonyms:PLA2G16, AdPLA, H-REV107, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3
Background:
UniProt Protein Function:PLA2G16: Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N- and O- acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity. Belongs to the H-rev107 family.
UniProt Protein Details:

Protein type:EC 3.1.1.4; EC 3.1.1.32; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; cytosol

Molecular Function:phospholipase A2 activity; protein binding; phospholipase A1 activity

Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; negative regulation of cell cycle

UniProt Code:P53816
NCBI GenInfo Identifier:75517991
NCBI Gene ID:11145
NCBI Accession:
UniProt Related Accession:P53816,Q3MI98
Molecular Weight:21,441 Da
NCBI Full Name:PLA2G16 protein
NCBI Synonym Full Names:phospholipase A2, group XVI
NCBI Official Symbol:PLA2G16  
NCBI Official Synonym Symbols:AdPLA; HRSL3; HRASLS3; HREV107; HREV107-1; HREV107-3; MGC118754; H-REV107-1  
NCBI Protein Information:group XVI phospholipase A2; OTTHUMP00000237069; adipose-specific PLA2; HRAS-like suppressor 1; HRAS-like suppressor 3; H-rev 107 protein homolog; Ca-independent phospholipase A1/2; adipose-specific phospholipase A2; renal carcinoma antigen NY-REN-65
UniProt Protein Name:PLA2G16 protein
Protein Family:HRAS-like suppressor
UniProt Gene Name:PLA2G16  
UniProt Entry Name:Q3MI98_HUMAN
Anti-PLA2G16 Antibody (CAB16018)Western blot analysis of extracts of various cell lines, using PLA2G16 antibody (CAB16018) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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system_update_altDatasheetHuman PLA2G16 Recombinant Protein Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ova