Developmental Biology
Anti-PIWIL-1 Antibody (CAB6823)
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- SKU:
- CAB6823
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | PIWIL1 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB6823 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 390-690 of human PIWIL1 (NP_004755.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 390-690 of human PIWIL1 (NP_004755.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TGLT DKMR NDFN VMKD LAVH TRLT PEQR QREV GRLI DYIH KNDN VQRE LRDW GLSF DSNL LSFS GRIL QTEK IHQG GKTF DYNP QFAD WSKE TRGA PLIS VKPL DNWL LIYT RRNY EAAN SLIQ NLFK VTPA MGMQ MRKA IMIE VDDR TEAY LRVL QQKV TADT QIVV CLLS SNRK DKYD AIKK YLCT DCPT PSQC VVAR TLGK QQTV MAIA TKIA LQMN CKMG GELW RVDI PLKL VMIV GIDC YHDM TAGR RSIA GFVA SINE GMTR WFSR CIFQ DRGQ ELVD GLKV CLQA ALRA WNSC N |
| Gene ID: | 9271 |
| Uniprot: | Q96J94 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 89kDa/94kDa/98kDa |
| Observed MW: | Refer to figures |
| Synonyms: | PIWIL1, CT80.1, HIWI, MIWI, PIWI |
| Background: | This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| UniProt Code: | Q96J94 |
| NCBI GenInfo Identifier: | 300244501 |
| NCBI Gene ID: | 9271 |
| NCBI Accession: | NP_001177900.1 |
| UniProt Related Accession: | Q96J94 |
| Molecular Weight: | Observed: 90 kDaPredicted: 99 kDa |
| NCBI Full Name: | piwi-like protein 1 isoform 2 |
| NCBI Synonym Full Names: | piwi like RNA-mediated gene silencing 1 |
| NCBI Official Symbol: | PIWIL1 |
| NCBI Official Synonym Symbols: | HIWI; MIWI; PIWI; CT80.1 |
| NCBI Protein Information: | piwi-like protein 1 |
| UniProt Protein Name: | Piwi-like protein 1 |
| UniProt Gene Name: | PIWIL1 |
| UniProt Entry Name: | PIWL1_HUMAN |
 | Immunofluorescence analysis of U2OS cells using PIWIL1 antibody (CAB6823) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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