Cell Biology Antibodies 15
Anti-PIGU Antibody (CAB18538)
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- SKU:
- CAB18538
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PIGU Antibody |
| Antibody SKU: | CAB18538 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PIGU. |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, 293T, Rat brain |
| Immunogen: | Recombinant protein of human PIGU. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 128869 |
| Uniprot: | Q9H490 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 50kDa |
 | Western blot - PIGU Rabbit pAb (CAB18538) |
| Synonyms: | CDC91L1, GAB1, PIGU |
| Background: |
| UniProt Protein Function: | PIGU: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI. Belongs to the PIGU family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 20q11.22 Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; integral to endoplasmic reticulum membrane; membrane; plasma membrane Molecular Function:GPI-anchor transamidase activity Biological Process: attachment of GPI anchor to protein; GPI anchor biosynthetic process; regulation of JAK-STAT cascade |
| NCBI Summary: | The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H490 |
| NCBI GenInfo Identifier: | 29336947 |
| NCBI Gene ID: | 128869 |
| NCBI Accession: | Q9H490.3 |
| UniProt Secondary Accession: | Q9H490,Q7Z489, Q8N2F2, |
| UniProt Related Accession: | Q9H490 |
| Molecular Weight: | 47,611 Da |
| NCBI Full Name: | Phosphatidylinositol glycan anchor biosynthesis class U protein |
| NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis class U |
| NCBI Official Symbol: | PIGU |
| NCBI Official Synonym Symbols: | GAB1; CDC91L1 |
| NCBI Protein Information: | phosphatidylinositol glycan anchor biosynthesis class U protein |
| UniProt Protein Name: | Phosphatidylinositol glycan anchor biosynthesis class U protein |
| UniProt Synonym Protein Names: | Cell division cycle protein 91-like 1; Protein CDC91-like 1; GPI transamidase component PIG-U |
| Protein Family: | Piguamerin |
| UniProt Gene Name: | PIGU |
| UniProt Entry Name: | PIGU_HUMAN |
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