Cell Biology Antibodies 18
Anti-PIF1 Antibody (CAB18398)
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- SKU:
- CAB18398
- Product Type:
- Antibody
- Reactivity:
- Plant - Arabidopsis
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PIF1 Antibody |
| Antibody SKU: | CAB18398 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Arabidopsis thaliana |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of Arabidopsis thaliana PIF1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Arabidopsis thaliana |
| Positive Samples: |
| Immunogen: | Recombinant protein of Arabidopsis thaliana PIF1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 816538 |
| Uniprot: | Q8GZM7 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | PIF1 |
| Background: |
| UniProt Protein Function: | Transcription activator. Regulates negatively chlorophyll biosynthesis and seed germination in the dark, and lightinduced degradation of PIF1 relieves this negative regulation to promote photomorphogenesis. Binds to the G-box motif (5'-CACGTG-3') found in many light-regulated promoters. Promotes the expression of SOM, and thus modulates responses to abscisic acid (ABA) and gibberellic acid (GA). |
| NCBI Summary: | Encodes a novel Myc-related bHLH transcription factor that has transcriptional activation activity in the dark. It is a key negative regulator of phytochrome-mediated seed germination and acts by inhibiting chlorophyll biosynthesis, light-mediated suppression of hypocotyl elongation and far-red light-mediated suppression of seed germination, and promoting negative gravitropism in hypocotyls. Light reduces this activity in a phy-dependent manner. The protein preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB), is physically associated with APRR1/TOC1 and is degraded in red (R) and far-red (FR) light through the ubiquitin (ub)-26S proteasome pathway to optimize photomorphogenic development in Arabidopsis. It also negatively regulates GA3 oxidase expression. |
| UniProt Code: | Q8GZM7 |
| NCBI GenInfo Identifier: | 334184322 |
| NCBI Gene ID: | 816538 |
| NCBI Accession: | NP_001189559.1 |
| UniProt Secondary Accession: | Q8GZM7,Q0WQ83, Q3EBY0, Q9SL63, |
| UniProt Related Accession: | Q8GZM7 |
| Molecular Weight: | 44,715 Da |
| NCBI Full Name: | phytochrome interacting factor 3-like 5 |
| NCBI Official Symbol: | PIL5 |
| NCBI Official Synonym Symbols: | PHY-INTERACTING FACTOR 1; phytochrome interacting factor 3-like 5; PIF1; T2G17.2; T2G17_2 |
| NCBI Protein Information: | phytochrome interacting factor 3-like 5 |
| UniProt Protein Name: | Transcription factor PIF1 |
| UniProt Synonym Protein Names: | Basic helix-loop-helix protein 15; AtbHLH15; bHLH 15; Protein PHY-INTERACTING FACTOR 1; Protein PHYTOCHROME INTERACTING FACTOR 3-LIKE 5; Transcription factor EN 101; bHLH transcription factor bHLH015 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | PIF1 |
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