Description
Product Name: | Phospho-TDP-43/TARDB-S409/S410 Rabbit pAb |
Product Code: | CABP1241 |
Size: | 50uL, 100uL |
Synonyms: | ALS10, TDP-43, TARDBP, TDP43 |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S409/S410 of Human TDP-43/TARDB. |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S409/S410 of Human TDP-43/TARDB. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MSEY IRVT EDEN DEPI EIPS EDDG TVLL STVT AQFP GACG LRYR NPVS QCMR GVRL VEGI LHAP DAGW GNLV YVVN YPKD NKRK MDET DASS AVKV KRAV QKTS DLIV LGLP WKTT EQDL KEYF STFG EVLM VQVK KDLK TGHS KGFG FVRF TEYE TQVK VMSQ RHMI DGRW CDCK LPNS KQSQ DEPL RSRK VFVG RCTE DMTE DELR EFFS QYGD VMDV FIPK PFRA FAFV TFAD DQIA QSLC GEDL IIKG ISVH ISNA |
Gene ID: | 23435 |
Uniprot: | Q13148 |
Cellular Location: | Nucleus |
Calculated MW: | 31kDa/44kDa |
Observed MW: | Refer to figures |
NCBI Summary: | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13148 |
NCBI GenInfo Identifier: | 20140568 |
NCBI Gene ID: | 23435 |
NCBI Accession: | |
UniProt Related Accession: | Q13148 |
Molecular Weight: | 44 |
NCBI Full Name: | TAR DNA-binding protein 43 |
NCBI Synonym Full Names: | TAR DNA binding protein |
NCBI Official Symbol: | TARDBP |
NCBI Official Synonym Symbols: | ALS10; TDP-43 |
NCBI Protein Information: | TAR DNA-binding protein 43 |
UniProt Protein Name: | |
UniProt Gene Name: |