Cell Biology Antibodies 15
Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Antibody (CABP1049)
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- SKU:
- CABP1049
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
Description
| Antibody Name: | Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Antibody |
| Antibody SKU: | CABP1049 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S474 of human PAK4 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | NIH/3T3, C6 |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S474 of human PAK4 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10298/57144/56924 |
| Uniprot: | O96013(PAK4-Antigen), Q9P286(PAK5), Q9NQU5(PAK6) |
| Cellular Location: | |
| Calculated MW: | 64, 80, 75 kDa |
| Observed MW: | 64KDa/75KDa |
 | Western blot - Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Rabbit mAb (CABP1049) |
| Synonyms: | |
| Background: | PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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