Epigenetics & Nuclear Signaling Antibodies 5
Anti-Phospho-JunD-S255 Antibody (CABP1142)
- SKU:
- CABP1142
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Antibody Name: | Anti-Phospho-JunD-S255 Antibody |
Antibody SKU: | CABP1142 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S255 of human JunD |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | NIH/3T3 |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S255 of human JunD |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 3727 |
Uniprot: | P17535 |
Cellular Location: | |
Calculated MW: | 38, 42kDa |
Observed MW: | 38KDa/42KDa |
Synonyms: | AP-1 |
Background: | The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013] |
UniProt Protein Function: | JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily. |
UniProt Protein Details: | Protein type:Transcription factor; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: chromatin; nuclear chromatin; nucleus; transcription factor complex Molecular Function:enzyme binding; ligand-dependent nuclear receptor binding; protein binding; transcription coactivator activity; transcription factor binding Biological Process: aging; cellular response to hormone stimulus; circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; osteoblast development; positive regulation of cell differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to light stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to peptide hormone stimulus; response to radiation; transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013] |
UniProt Code: | P17535 |
NCBI GenInfo Identifier: | 229462969 |
NCBI Gene ID: | 3727 |
NCBI Accession: | P17535.3 |
UniProt Secondary Accession: | P17535,Q53EK9, |
UniProt Related Accession: | P17535 |
Molecular Weight: | 35,174 Da |
NCBI Full Name: | Transcription factor jun-D |
NCBI Synonym Full Names: | jun D proto-oncogene |
NCBI Official Symbol: | JUND |
NCBI Official Synonym Symbols: | AP-1 |
NCBI Protein Information: | transcription factor jun-D |
UniProt Protein Name: | Transcription factor jun-D |
Protein Family: | Transcription factor |
UniProt Gene Name: | JUND |
UniProt Entry Name: | JUND_HUMAN |