Cell Biology Antibodies 15
Anti-Phospho-Histone H2A-S129 Antibody (CABP1063)
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- SKU:
- CABP1063
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Description
| Antibody Name: | Anti-Phospho-Histone H2A-S129 Antibody |
| Antibody SKU: | CABP1063 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A. |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 851811 |
| Uniprot: | P04911 |
| Cellular Location: | |
| Calculated MW: | 14kDa |
| Observed MW: |
 | Immunohistochemistry - Phospho-Histone H2A-S129 Rabbit pAb (CABP1063) |
| Synonyms: | H2A1, SPT11 |
| Background: | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| UniProt Protein Function: | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| UniProt Code: | P04911 |
| NCBI GenInfo Identifier: | 398366187 |
| NCBI Gene ID: | 851811 |
| NCBI Accession: | NP_010511.3 |
| UniProt Secondary Accession: | P04911,D6VSK7, |
| UniProt Related Accession: | P04911 |
| Molecular Weight: | 13,989 Da |
| NCBI Full Name: | histone H2A |
| NCBI Official Symbol: | HTA1 |
| NCBI Official Synonym Symbols: | H2A1; SPT11 |
| NCBI Protein Information: | histone H2A |
| UniProt Protein Name: | Histone H2A.1 |
| Protein Family: | Histone |
| UniProt Gene Name: | HTA1 |
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