Cell Biology Antibodies 17
Anti-Phospho-ERK1-T202 + ERK2-T185 Antibody (CABP0485)
- SKU:
- CABP0485
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-Phospho-ERK1-T202 + ERK2-T185 Antibody |
Antibody SKU: | CABP0485 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human Phospho-ERK1 (T202) + ERK2 (T185). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Jurkat, NIH/3T3 |
Immunogen: | A synthesized peptide derived from human Phospho-ERK1 (T202) + ERK2 (T185). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 5594/5595 |
Uniprot: | P28482/P27361 |
Cellular Location: | |
Calculated MW: | 42, 44kDa |
Observed MW: | 44KDa |
Synonyms: | H3.4, H3/g, H3FT, H3t, H3/A, H3FA, ERK1 / ERK2 |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |