Anti-Phospho-CGAS-S420 Antibody (CABP1228)
- SKU:
- CABP1228
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- E330016A19Rik
- Synonyms:
- cGAS
Description
| Product Name: | Phospho-CGAS-S420 Rabbit pAb |
| Product Code: | CABP1228 |
| Size: | 50uL, 100uL |
| Synonyms: | E330016A19Rik, cGAS |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | 293T, C6 |
| Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 214763 |
| Uniprot: | Q8C6L5 |
| Observed MW: | 62KDa |
| Background: | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
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