Description
| Product Name: | PHF8 Rabbit mAb |
| Product Code: | CAB19780 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | JHDM1F, KDM7B, MRXSSD, ZNF422 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PHF8 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, C2C12, Mouse thymus |
| Immunogen: | A synthesized peptide derived from human PHF8 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23133 |
| Uniprot: | Q9UPP1 |
| Calculated MW: | 140kDa |
| Observed MW: | 140KDa |
| Background: | The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] |