Epigenetics & Nuclear Signaling Antibodies 4

Anti-PHF11 Antibody (CAB7803)

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SKU:
CAB7803
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-PHF11 Antibody
Antibody SKU:CAB7803
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human PHF11 (NP_001035533.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:MCF7, SW480, Raji, Mouse spleen, Mouse thymus, Rat spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human PHF11 (NP_001035533.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAQA SPPR PERV LGAS SPEA RPAQ EALL LPTG VFQV AEKM EKRT CALC PKDV EYNV LYFA QSEN IAAH ENCL LYSS GLVE CEDQ DPLN PDRS FDVE SVKK EIQR GRKL KCKF CHKR GATV GCDL KNCN KNYH FFCA KKDD AVPQ SDGV RGIY KLLC QQHA QFPI IAQS AKFS GVKR KRGR KKPL SGNH VQPP ETMK CNTF IRQV KEEH GRHT DATV KVPF LKKC KEAG LLNY LLEE ILDK VHSI PEKL MDET TSES DYEE IGSA LFDC RLFE DTFV NFQA AIEK KIHA SQQR
Gene ID:51131
Uniprot:Q9UIL8
Cellular Location:Nucleus
Calculated MW:33kDa/37kDa
Observed MW:34kDa
Synonyms:PHF11, APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34
Background:This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:PHF11: Positive regulator of Th1-type cytokine gene expression. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 13q14.2

Cellular Component: nucleus

Molecular Function:zinc ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent

Disease: Asthma, Susceptibility To; Ige Responsiveness, Atopic

NCBI Summary:This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
UniProt Code:Q9UIL8
NCBI GenInfo Identifier:259016330
NCBI Gene ID:51131
NCBI Accession:Q9UIL8.3
UniProt Related Accession:Q9UIL8
Molecular Weight:36kDa
NCBI Full Name:PHD finger protein 11
NCBI Synonym Full Names:PHD finger protein 11
NCBI Official Symbol:PHF11  
NCBI Official Synonym Symbols:APY; BCAP; IGEL; IGER; IGHER; NYREN34; NY-REN-34  
NCBI Protein Information:PHD finger protein 11
UniProt Protein Name:PHD finger protein 11
UniProt Synonym Protein Names:BRCA1 C-terminus-associated protein; Renal carcinoma antigen NY-REN-34
Protein Family:PHD finger protein
UniProt Gene Name:PHF11  
UniProt Entry Name:PHF11_HUMAN
Anti-PHF11 Antibody (CAB7803)Western blot analysis of extracts of various cell lines, using PHF11 antibody (CAB7803) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-PHF11 Antibody (CAB7803)Immunofluorescence analysis of A549 cells using PHF11 antibody (CAB7803). Blue: DAPI for nuclear staining.
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