Metabolism Antibodies 1
Anti-PGM3 Antibody (CAB15699)
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- SKU:
- CAB15699
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-PGM3 Antibody |
| Antibody SKU: | CAB15699 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM3 (NP_056414.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-549, Jurkat, Mouse thymus, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM3 (NP_056414.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDLG AITK YSAL HAKP NGLI LQYG TAGF RTKA EHLD HVMF RMGL LAVL RSKQ TKST IGVM VTAS HNPE EDNG VKLV DPLG EMLA PSWE EHAT CLAN AEEQ DMQR VLID ISEK EAVN LQQD AFVV IGRD TRPS SEKL SQSV IDGV TVLG GQFH DYGL LTTP QLHY MVYC RNTG GRYG KATI EGYY QKLS KAFV ELTK QASC SGDE YRSL KVDC ANGI GALK LREM EHYF SQGL SVQL FNDG SKGK LNHL CGAD FVKS HQKP PQGM EIKS NERC CSFD GDAD RIVY YYHD ADGH FHLI DGDK |
| Gene ID: | 5238 |
| Uniprot: | O95394 |
| Cellular Location: | |
| Calculated MW: | 59kDa/62kDa |
| Observed MW: | 65kDa |
| Synonyms: | PGM3, AGM1, IMD23, PAGM, PGM 3 |
| Background: | This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | PGM3: Interconverts GlcNAc-6-P and GlcNAc-1-P. Belongs to the phosphohexose mutase family. |
| UniProt Protein Details: | Protein type:EC 5.4.2.3; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Isomerase Chromosomal Location of Human Ortholog: 6q14.1-q15 Cellular Component: cytosol Molecular Function:phosphoacetylglucosamine mutase activity Biological Process: hemopoiesis; protein amino acid N-linked glycosylation; protein amino acid O-linked glycosylation; UDP-N-acetylglucosamine biosynthetic process Disease: Immunodeficiency 23 |
| NCBI Summary: | This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | O95394 |
| NCBI GenInfo Identifier: | 12643302 |
| NCBI Gene ID: | 5238 |
| NCBI Accession: | O95394.1 |
| UniProt Secondary Accession: | O95394,Q5JWR4, Q96J46, Q9H8G5, Q9NS94, Q9NTT6, Q9UFV5 B2RB65, B4DX94, D6RF12, E1P547, E9PF86, |
| UniProt Related Accession: | O95394 |
| Molecular Weight: | 62,941 Da |
| NCBI Full Name: | Phosphoacetylglucosamine mutase |
| NCBI Synonym Full Names: | phosphoglucomutase 3 |
| NCBI Official Symbol: | PGM3 |
| NCBI Official Synonym Symbols: | AGM1; PAGM; IMD23; PGM 3 |
| NCBI Protein Information: | phosphoacetylglucosamine mutase |
| UniProt Protein Name: | Phosphoacetylglucosamine mutase |
| UniProt Synonym Protein Names: | Acetylglucosamine phosphomutase |
| UniProt Gene Name: | PGM3 |
| UniProt Entry Name: | AGM1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PGM3 antibody (CAB15699) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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