Cell Biology Antibodies 13

Anti-PFAS Antibody (CAB17517)

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SKU:
CAB17517
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PFAS Antibody
Antibody SKU:CAB17517
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PFAS (NP_036525.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, 293T, Jurkat, Raji, U-87MG
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PFAS (NP_036525.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSPV LHFY VRPS GHEG AAPG HTRR KLQG KLPE LQGV ETEL CYNV NWTA EALP SAEE TKKL MWLF GCPL LLDD VARE SWLL PGSN DLLL EVGP RLNF STPT STNI VSVC RATG LGPV DRVE TTRR YRLS FAHP PSAE VEAI ALAT LHDR MTEQ HFPH PIQS FSPE SMPE PLNG PINI LGEG RLAL EKAN QELG LALD SWDL DFYT KRFQ ELQR NPST VEAF DLAQ SNSE HSRH WFFK GQLH VDGQ KLVH SLFE SIMS TQES SNPN NVLK FCDN SSAI QGKE VRFL RPED PTRP SRFQ QQQG
Gene ID:5198
Uniprot:O15067
Cellular Location:
Calculated MW:
Observed MW:145kDa
Anti-PFAS Antibody (CAB17517)Western blot - PFAS Polyclonal Antibody (CAB17517)
Synonyms:FGAMS, FGAR-AT, FGARAT, GATD8, PURL, PFAS
Background:Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]
UniProt Protein Function:PFAS: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
UniProt Protein Details:

Protein type:EC 6.3.5.3; Nucleotide Metabolism - purine; Ligase

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytoplasm; cytosol

Molecular Function:ATP binding; phosphoribosylformylglycinamidine synthase activity

Biological Process: glutamine metabolic process; purine nucleotide biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; ribonucleoside monophosphate biosynthetic process

NCBI Summary:Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]
UniProt Code:O15067
NCBI GenInfo Identifier:317373541
NCBI Gene ID:5198
NCBI Accession:O15067.4
UniProt Secondary Accession:O15067,A6H8V8,
UniProt Related Accession:O15067
Molecular Weight:144,734 Da
NCBI Full Name:Phosphoribosylformylglycinamidine synthase
NCBI Synonym Full Names:phosphoribosylformylglycinamidine synthase
NCBI Official Symbol:PFAS  
NCBI Official Synonym Symbols:PURL; FGAMS; FGARAT; FGAR-AT  
NCBI Protein Information:phosphoribosylformylglycinamidine synthase
UniProt Protein Name:Phosphoribosylformylglycinamidine synthase
UniProt Synonym Protein Names:Formylglycinamide ribonucleotide amidotransferase; FGAR amidotransferase; FGAR-AT; Formylglycinamide ribotide amidotransferase
UniProt Gene Name:PFAS  
UniProt Entry Name:PUR4_HUMAN
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