Anti-PERP Antibody (CAB5937)
- SKU:
- CAB5937
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KCP1
- Synonyms:
- KRTCAP1
- Synonyms:
- PIGPC1
- Synonyms:
- THW
- Synonyms:
- dJ496H19.1
- Research Area:
- Cell Death
Description
| Product Name: | PERP Rabbit mAb |
| Product Code: | CAB5937 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PERP |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, BxPC-3, A-431, Mouse liver, Mouse kidney, Rat lung, Rat liver |
| Immunogen: | A synthesized peptide derived from human PERP |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64065 |
| Uniprot: | Q96FX8 |
| Calculated MW: | 21kDa |
| Observed MW: | 21KDa |
| UniProt Protein Function: | PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 6q24 Cellular Component: cell junction; plasma membrane Biological Process: positive regulation of proteolysis; regulation of apoptosis |
| UniProt Code: | Q96FX8 |
| NCBI GenInfo Identifier: | 74751865 |
| NCBI Gene ID: | 64065 |
| NCBI Accession: | Q96FX8.1 |
| UniProt Secondary Accession: | Q96FX8,Q8IWS3, Q8N1J6, Q8NC16, Q9H1C5, Q9H230, B2RB73 E1P590, |
| UniProt Related Accession: | Q96FX8 |
| Molecular Weight: | 21,386 Da |
| NCBI Full Name: | p53 apoptosis effector related to PMP-22 |
| NCBI Synonym Full Names: | PERP, TP53 apoptosis effector |
| NCBI Official Symbol: | PERP |
| NCBI Official Synonym Symbols: | THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1 |
| NCBI Protein Information: | p53 apoptosis effector related to PMP-22 |
| UniProt Protein Name: | p53 apoptosis effector related to PMP-22 |
| UniProt Synonym Protein Names: | Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THW |
| Protein Family: | Perphorin |
| UniProt Gene Name: | PERP |
| UniProt Entry Name: | PERP_HUMAN |
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