Cell Death Antibodies 1
Anti-PERP Antibody (CAB15501)
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- SKU:
- CAB15501
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-PERP Antibody |
| Antibody SKU: | CAB15501 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human PERP (NP_071404.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HT-29, K562, Jurkat, Mouse thymus |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human PERP (NP_071404.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CGPQ MLVF LRVI GGLL ALAA VFQI ISLV IYPV KYTQ TFTL HANP AVTY IYNW AYGF GWAA TIIL IGCA FFFC CLPN YEDD LLGN AKPR YFYT SA |
| Gene ID: | 64065 |
| Uniprot: | Q96FX8 |
| Cellular Location: | Cell junction, Cell membrane, Multi-pass membrane protein, desmosome |
| Calculated MW: | 21kDa |
| Observed MW: | 17kDa |
| Synonyms: | PERP, KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1 |
| Background: |
| UniProt Protein Function: | PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 6q24 Cellular Component: cell junction; plasma membrane Biological Process: positive regulation of proteolysis; regulation of apoptosis |
| UniProt Code: | Q96FX8 |
| NCBI GenInfo Identifier: | 74751865 |
| NCBI Gene ID: | 64065 |
| NCBI Accession: | Q96FX8.1 |
| UniProt Secondary Accession: | Q96FX8,Q8IWS3, Q8N1J6, Q8NC16, Q9H1C5, Q9H230, B2RB73 E1P590, |
| UniProt Related Accession: | Q96FX8 |
| Molecular Weight: | 21,386 Da |
| NCBI Full Name: | p53 apoptosis effector related to PMP-22 |
| NCBI Synonym Full Names: | PERP, TP53 apoptosis effector |
| NCBI Official Symbol: | PERP |
| NCBI Official Synonym Symbols: | THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1 |
| NCBI Protein Information: | p53 apoptosis effector related to PMP-22 |
| UniProt Protein Name: | p53 apoptosis effector related to PMP-22 |
| UniProt Synonym Protein Names: | Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THW |
| Protein Family: | Perphorin |
| UniProt Gene Name: | PERP |
| UniProt Entry Name: | PERP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PERP antibody (CAB15501) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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