Anti-Peroxiredoxin 1 (PAG) Antibody (CAB19273)
- SKU:
- CAB19273
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PAG1
- Synonyms:
- CBP
- Synonyms:
- PAG
- Synonyms:
- phosphoprotein membrane anchor with glycosphingolipid microdomains 1
- Research Area:
- Immunology
Description
Product Name: | Peroxiredoxin 1 (PAG) Rabbit mAb |
Product Code: | CAB19273 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | PAG1, CBP, PAG, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human Peroxiredoxin 1 (Peroxiredoxin 1 (PAG)). |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Raji, SH-SY5Y, Mouse brain, Mouse spleen, Rat lung, Rat brain, Rat spleen |
Immunogen: | Recombinant protein of human Peroxiredoxin 1 (Peroxiredoxin 1 (PAG)). |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 55824 |
Uniprot: | Q9NWQ8 |
Calculated MW: | 80kDa |
Observed MW: | 76KDa |
UniProt Protein Function: | PAG: an ubiquitous type III transmembrane adaptor protein that binds to the tyrosine kinase CSK protein. It is thought to be involved in the regulation of T cell activation. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Adaptor/scaffold Chromosomal Location of Human Ortholog: 8q21.13 Cellular Component: plasma membrane; integral to membrane; lipid raft Molecular Function:protein binding; SH3/SH2 adaptor activity; SH2 domain binding Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of signal transduction; signal transduction; negative regulation of T cell activation; T cell receptor signaling pathway; regulation of T cell activation |
NCBI Summary: | The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NWQ8 |
NCBI GenInfo Identifier: | 63054864 |
NCBI Gene ID: | 55824 |
NCBI Accession: | NP_060910.3 |
UniProt Secondary Accession: | Q9NWQ8,Q3U1F9, Q9JM80, |
UniProt Related Accession: | Q9NWQ8 |
Molecular Weight: | 46,981 Da |
NCBI Full Name: | phosphoprotein associated with glycosphingolipid-enriched microdomains 1 |
NCBI Synonym Full Names: | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
NCBI Official Symbol: | PAG1 |
NCBI Official Synonym Symbols: | CBP; PAG |
NCBI Protein Information: | phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Csk-binding protein; phosphoprotein associated with glycosphingolipid microdomains 1; transmembrane adapter protein PAG; transmembrane adaptor protein PAG; transmembrane phosphoprot |
UniProt Protein Name: | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 |
UniProt Synonym Protein Names: | Csk-binding protein; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp |
Protein Family: | CBP3-like protein |
UniProt Gene Name: | PAG1 |
UniProt Entry Name: | PHAG1_HUMAN |