Metabolism Antibodies 3
Anti-Perilipin A Antibody (CAB4758)
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- SKU:
- CAB4758
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FPLD4
- Synonyms:
- PERI
- Synonyms:
- PLIN
- Research Area:
- Metabolism
Description
| Product Name: | Perilipin A Rabbit mAb |
| Product Code: | CAB4758 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | FPLD4, PERI, PLIN |
| Applications: | WB, IHC, IF |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Perilipin A |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse testis, Mouse kidney, Mouse heart, Rat liver |
| Immunogen: | A synthesized peptide derived from human Perilipin A |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5346 |
| Uniprot: | O60240 |
| Calculated MW: | 62kDa |
| Observed MW: | 70KDa |
| UniProt Protein Function: | perilipin 1: an adipocyte protein of the peripilin family. A modulator of adipocyte lipid metabolism, coating lipid storage droplets to protect them from being broken down by hormone-sensitive lipase. A major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis. |
| UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 15q26 Cellular Component: endoplasmic reticulum; lipid particle; cytosol Molecular Function:lipid binding Biological Process: triacylglycerol catabolic process; lipid metabolic process Disease: Lipodystrophy, Familial Partial, Type 4 |
| NCBI Summary: | The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009] |
| UniProt Code: | O60240 |
| NCBI GenInfo Identifier: | 229462739 |
| NCBI Gene ID: | 5346 |
| NCBI Accession: | O60240.2 |
| UniProt Secondary Accession: | O60240,Q8N5Y6, |
| UniProt Related Accession: | O60240 |
| Molecular Weight: | 55,990 Da |
| NCBI Full Name: | Perilipin-1 |
| NCBI Synonym Full Names: | perilipin 1 |
| NCBI Official Symbol: | PLIN1 |
| NCBI Official Synonym Symbols: | PERI; PLIN; FPLD4 |
| NCBI Protein Information: | perilipin-1; lipid droplet-associated protein |
| UniProt Protein Name: | Perilipin-1 |
| UniProt Synonym Protein Names: | Lipid droplet-associated protein |
| Protein Family: | Perilipin |
| UniProt Gene Name: | PLIN1 |
| UniProt Entry Name: | PLIN1_HUMAN |
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