Cell Cycle Antibodies 1
Anti-PELO Antibody (CAB4776)
- SKU:
- CAB4776
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PELO
- Synonyms:
- CGI-17
- Synonyms:
- PRO1770
- Research Area:
- Cell Cycle
Description
| Product Name: | PELO Rabbit pAb |
| Product Code: | CAB4776 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | PELO, CGI-17, PRO1770 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PELO (NP_057030.3). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, LO2, 293T, Mouse liver, Mouse pancreas, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PELO (NP_057030.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKLV RKNI EKDN AGQV TLVP EEPE DMWH TYNL VQVG DSLR ASTI RKVQ TESS TGSV GSNR VRTT LTLC VEAI DFDS QACQ LRVK GTNI QENE YVKM GAYH TIEL EPNR QFTL AKKQ WDSV VLER IEQA CDPA WSAD VAAV VMQE GLAH ICLV TPSM TLTR AKVE VNIP RKRK GNCS QHDR ALER FYEQ VVQA IQRH IHFD |
| Gene ID: | 53918 |
| Uniprot: | Q9BRX2 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 43kDa |
| Observed MW: | 43kDa |
| UniProt Protein Function: | PELO: Required for normal chromosome segregation during cell division and genomic stability. May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily. |
| UniProt Protein Details: | Protein type:EC 3.1.-.-; Hydrolase Chromosomal Location of Human Ortholog: 5q11.2 Cellular Component: cytoplasm; nucleus Molecular Function:endonuclease activity; metal ion binding Biological Process: cell proliferation; cell division; cell cycle; chromosome organization and biogenesis |
| NCBI Summary: | This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BRX2 |
| NCBI GenInfo Identifier: | 322510057 |
| NCBI Gene ID: | 53918 |
| NCBI Accession: | Q9BRX2.2 |
| UniProt Secondary Accession: | Q9BRX2,Q9GZS6, Q9Y306, |
| UniProt Related Accession: | Q9BRX2 |
| Molecular Weight: | 385 |
| NCBI Full Name: | Protein pelota homolog |
| NCBI Synonym Full Names: | pelota homolog (Drosophila) |
| NCBI Official Symbol: | PELO |
| NCBI Official Synonym Symbols: | CGI-17; PRO1770 |
| NCBI Protein Information: | protein pelota homolog |
| UniProt Protein Name: | Protein pelota homolog |
| Protein Family: | Pelovaterin |
| UniProt Gene Name: | PELO |
| UniProt Entry Name: | PELO_HUMAN |
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