Metabolism Antibodies 2

Anti-PDSS2 Antibody (CAB16557)

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SKU:
CAB16557
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-PDSS2 Antibody
Antibody SKU:CAB16557
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-399 of human PDSS2 (NP_065114.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:A-375
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-399 of human PDSS2 (NP_065114.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDLV QGVY HENS TSKE SYIT DDIG ISTW KEQT FLSH GALL AKSC QAAM ELAK HDAE VQNM AFQY GKHM AMSH KINS DVQP FIKE KTSD SMTF NLNS APVV LHQE FLGR DLWI KQIG EAQE KGRL DYAK LRER IKAG KGVT SAID LCRY HGNK ALEA LESF PPSE ARSA LENI VFAV TRFS
Gene ID:57107
Uniprot:Q86YH6
Cellular Location:Mitochondrion
Calculated MW:26kDa/44kDa
Observed MW:30kDa
Synonyms:PDSS2, C6orf210, COQ10D3, DLP1, bA59I9.3, hDLP1
Background:The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
UniProt Protein Function:PYY: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: extracellular space; extracellular region

Molecular Function:neuropeptide hormone activity; protein binding; G-protein-coupled receptor binding; hormone activity

Biological Process: cell proliferation; G-protein coupled receptor protein signaling pathway; cell-cell signaling; eating behavior; neuropeptide signaling pathway; digestion; regulation of appetite; feeding behavior; cytoskeleton organization and biogenesis; cell motility

Disease: Obesity

UniProt Code:Q86YH6
NCBI GenInfo Identifier:169808399
NCBI Gene ID:57107
NCBI Accession:NP_065114
UniProt Secondary Accession:Q86YH6,Q86YH6,
UniProt Related Accession:Q86YH6
Molecular Weight:26,377 Da
NCBI Full Name:decaprenyl-diphosphate synthase subunit 2
NCBI Synonym Full Names:prenyl (decaprenyl) diphosphate synthase, subunit 2
NCBI Official Symbol:PDSS2  
NCBI Official Synonym Symbols:DLP1; hDLP1; COQ10D3; C6orf210; bA59I9.3  
NCBI Protein Information:decaprenyl-diphosphate synthase subunit 2; all-trans-decaprenyl-diphosphate synthase subunit 2; decaprenyl pyrophosphate synthase subunit 2; decaprenyl pyrophosphate synthetase subunit 2; subunit 2 of decaprenyl diphosphate synthase
UniProt Protein Name:Peptide YY
UniProt Synonym Protein Names:PYY-I; Peptide tyrosine tyrosineCleaved into the following chain:Peptide YY(3-36); Alternative name(s):; PYY-II
Protein Family:Peptide
UniProt Gene Name:PYY  
UniProt Entry Name:PYY_HUMAN
Anti-PDSS2 Antibody (CAB16557)Western blot analysis of extracts of A-375 cells, using PDSS2 antibody (CAB16557) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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