Cell Biology Antibodies 5
Anti-PDIA5 Antibody (CAB14476)
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- SKU:
- CAB14476
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PDIA5 Antibody |
| Antibody SKU: | CAB14476 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-140 of human PDIA5 (NP_006801.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-140 of human PDIA5 (NP_006801.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SSAK VSSL IERI SDPK DLKK LLRT RNNV LVLY SKSE VAAE NHLR LLST VAQA VKGQ GTIC WVDC GDAE SRKL CKKM KVDL SPKD KKVE LFHY QDGA FHTE YNRA VTFK SIVA FLKD PKG |
| Gene ID: | 10954 |
| Uniprot: | Q14554 |
| Cellular Location: | Endoplasmic reticulum lumen |
| Calculated MW: | 30kDa/59kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | PDIA5, PDIR |
| Background: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants. |
| UniProt Protein Function: | PDIA5: Belongs to the protein disulfide isomerase family. |
| UniProt Protein Details: | Protein type:EC 5.3.4.1; Isomerase; Chaperone; Oxidoreductase; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 3q21.1 Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum membrane Molecular Function:oxidoreductase activity; protein binding; protein disulfide isomerase activity Biological Process: protein folding |
| UniProt Code: | Q14554 |
| NCBI GenInfo Identifier: | 2501208 |
| NCBI Gene ID: | 10954 |
| NCBI Accession: | Q14554.1 |
| UniProt Secondary Accession: | Q14554,Q9BV43, D3DN95, |
| UniProt Related Accession: | Q14554 |
| Molecular Weight: | 30,124 Da |
| NCBI Full Name: | Protein disulfide-isomerase A5 |
| NCBI Synonym Full Names: | protein disulfide isomerase family A member 5 |
| NCBI Official Symbol: | PDIA5 |
| NCBI Official Synonym Symbols: | PDIR |
| NCBI Protein Information: | protein disulfide-isomerase A5 |
| UniProt Protein Name: | Protein disulfide-isomerase A5 |
| UniProt Synonym Protein Names: | Protein disulfide isomerase-related protein |
| Protein Family: | Protein disulfide-isomerase |
| UniProt Gene Name: | PDIA5 |
| UniProt Entry Name: | PDIA5_HUMAN |
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