Cell Biology Antibodies 11
Anti-PDE4DIP Antibody (CAB7765)
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- SKU:
- CAB7765
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PDE4DIP Antibody |
| Antibody SKU: | CAB7765 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human PDE4DIP (NP_071754.3). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human PDE4DIP (NP_071754.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKGT DSGS CCRR RCDF GCCC RASR RAHY TPYR SGDA TRTP QSPR QTPS RERR RPEP AGSW AAAA EEEE AAAA ATPW MRDY FAED DGEM VPRT SHTA AFLS DTKD RGPP VQSQ IWRS GEKV PFVQ TYSL RAFE KPPQ VQTQ ALRD FEKH LNDL KKEN FSLK LRIY FLEE RMQQ KYEA SRED IYKR NIEL KVEV ESLK RELQ DKKQ HLDK TWAD VENL NSQN EAEL RRQF EERQ QETE HVYE LLEN KIQL LQEE SRLA KNEA ARMA ALVE AEKE CNLE LSEK LKGV TKNW EDVP GDQV KPDQ YTEA LAQR DK |
| Gene ID: | 9659 |
| Uniprot: | Q5VU43 |
| Cellular Location: | Cytoplasm, Golgi apparatus, Nucleus, centrosome, cytoskeleton, microtubule organizing center |
| Calculated MW: | 20-36kDa/112-128kDa/254-267kDa |
| Observed MW: | 265kDa |
| Synonyms: | PDE4DIP, CMYA2, MMGL |
| Background: | The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. |
| UniProt Code: | Q5VU43 |
| NCBI GenInfo Identifier: | 305410866 |
| NCBI Gene ID: | 653513 |
| NCBI Accession: | NP_001182190 |
| Molecular Weight: | |
| NCBI Full Name: | myomegalin isoform 7 |
| NCBI Official Symbol: | LOC653513 |
| NCBI Protein Information: | myomegalin; uncharacterized protein LOC653513 |
| UniProt Protein Name: | Myomegalin |
| UniProt Synonym Protein Names: | Cardiomyopathy-associated protein 2; Phosphodiesterase 4D-interacting protein |
| UniProt Gene Name: | PDE4DIP |
| UniProt Entry Name: | MYOME_HUMAN |
 | Western blot analysis of extracts of mouse skeletal muscle, using PDE4DIP antibody (CAB7765) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded rat heart using PDE4DIP antibody (CAB7765) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human kidney using PDE4DIP antibody (CAB7765) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using PDE4DIP antibody (CAB7765) at dilution of 1:100 (40x lens). |
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