Cell Biology Antibodies 4
Anti-PDCL Antibody (CAB13722)
- SKU:
- CAB13722
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-PDCL Antibody |
Antibody SKU: | CAB13722 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human PDCL (NP_005379.3). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | 293T, OVCAR3, HepG2 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human PDCL (NP_005379.3). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MTTL DDKL LGEK LQYY YSSS EDED SDHE DKDR GRCA PASS SVPA EAEL AGEG ISVN TGPK GVIN DWRR FKQL ETEQ REEQ CREM ERLI KKLS MTCR SHLD EEEE QQKQ KDLQ EKIS GKMT LKEF AIMN EDQD DEEF LQQY RKQR MEEM RQQL HKGP QFKQ VFEI SSGE GFLD MIDK EQKS IVIM VHIY EDGI PGTE AMNG CMIC LAAE YPAV KFCK VKSS VIGA SSQF TRNA LPAL LIYK GGEL IGNF VRVT DQLG DDFF AVDL EAFL QEFG LLPE KEVL VLTS VRNS ATCH SEDS DLEI D |
Gene ID: | 5082 |
Uniprot: | Q13371 |
Cellular Location: | |
Calculated MW: | 24kDa/34kDa |
Observed MW: | 34kDa |
Synonyms: | PDCL, PhLP |
Background: | Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. |
UniProt Protein Function: | PhLP: a member of the phosducin family of G-protein beta-gamma regulators. Shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. Two splice variants have been described. |
UniProt Protein Details: | Protein type:G protein regulator, misc. Chromosomal Location of Human Ortholog: 9q12-q13 Cellular Component: cytoplasm Molecular Function:protein binding; receptor signaling protein activity; protein complex binding Biological Process: protein folding; visual perception; signal transduction; regulation of G-protein coupled receptor protein signaling pathway |
NCBI Summary: | Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13371 |
NCBI GenInfo Identifier: | 27808673 |
NCBI Gene ID: | 5082 |
NCBI Accession: | Q13371.3 |
UniProt Secondary Accession: | Q13371,Q63737, Q9DBX2, Q2HJA9, |
UniProt Related Accession: | Q13371 |
Molecular Weight: | 34282 |
NCBI Full Name: | Phosducin-like protein |
NCBI Synonym Full Names: | phosducin like |
NCBI Official Symbol: | PDCL |
NCBI Official Synonym Symbols: | PhLP |
NCBI Protein Information: | phosducin-like protein |
UniProt Protein Name: | Phosducin-like protein |
Protein Family: | Phosducin-like protein |
UniProt Gene Name: | PDCL |
UniProt Entry Name: | PHLP_HUMAN |
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