Cell Death Antibodies 1
Anti-PDCD7 Antibody (CAB12133)
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- SKU:
- CAB12133
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-PDCD7 Antibody |
| Antibody SKU: | CAB12133 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-485 of human PDCD7 (NP_005698.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HT-29, HeLa, Jurkat, MCF7, Rat thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-485 of human PDCD7 (NP_005698.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EKEK ILLQ KREI ESKL FGDP DEFP LAHL LEPF RQYY LQAE HSLP ALIQ IRHD WDQY LVPS DHPK GNFV PQGW VLPP LPSN DIWA TAVK LH |
| Gene ID: | 10081 |
| Uniprot: | Q8N8D1 |
| Cellular Location: | Nucleus |
| Calculated MW: | 54kDa |
| Observed MW: | 60kDa |
| Synonyms: | PDCD7, ES18, HES18 |
| Background: | This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. |
| UniProt Protein Function: | PDCD7: Promotes apoptosis when overexpressed. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 15q22.31 Cellular Component: nucleoplasm; U12-dependent spliceosome Biological Process: nuclear mRNA splicing, via spliceosome; response to glucocorticoid stimulus; RNA splicing |
| NCBI Summary: | This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q8N8D1 |
| NCBI GenInfo Identifier: | 38258174 |
| NCBI Gene ID: | 10081 |
| NCBI Accession: | Q8N8D1.1 |
| UniProt Secondary Accession: | Q8N8D1,Q96AK8, Q9Y6D7, |
| UniProt Related Accession: | Q8N8D1 |
| Molecular Weight: | 55kDa |
| NCBI Full Name: | Programmed cell death protein 7 |
| NCBI Synonym Full Names: | programmed cell death 7 |
| NCBI Official Symbol: | PDCD7 |
| NCBI Official Synonym Symbols: | ES18; HES18 |
| NCBI Protein Information: | programmed cell death protein 7 |
| UniProt Protein Name: | Programmed cell death protein 7 |
| UniProt Synonym Protein Names: | ES18; hES18 |
| Protein Family: | Programmed cell death protein |
| UniProt Gene Name: | PDCD7 |
 | Western blot analysis of extracts of various cell lines, using PDCD7 antibody (CAB12133) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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