Cell Death Antibodies 2
Anti-PDCD5 Antibody (CAB7298)
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- SKU:
- CAB7298
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-PDCD5 Antibody |
| Antibody SKU: | CAB7298 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human PDCD5 (NP_004699.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse heart, Mouse testis, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human PDCD5 (NP_004699.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADE ELEA LRRQ RLAE LQAK HGDP GDAA QQEA KHRE AEMR NSIL AQVL DQSA RARL SNLA LVKP EKTK AVEN YLIQ MARY GQLS EKVS EQGL IEIL KKVS QQTE KTTT VKFN RRKV MDSD EDDD Y |
| Gene ID: | 9141 |
| Uniprot: | O14737 |
| Cellular Location: | |
| Calculated MW: | 14kDa |
| Observed MW: | 14kDa |
| Synonyms: | PDCD5, TFAR19 |
| Background: | This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 |
| UniProt Protein Function: | PDCD5: May function in the process of apoptosis. Belongs to the PDCD5 family. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 19q13.11 Cellular Component: cytoplasm; nucleus Molecular Function:heparin binding; protein binding; DNA binding; beta-tubulin binding Biological Process: negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of caspase activity |
| NCBI Summary: | This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010] |
| UniProt Code: | O14737 |
| NCBI GenInfo Identifier: | 6226219 |
| NCBI Gene ID: | 9141 |
| NCBI Accession: | O14737.3 |
| UniProt Related Accession: | O14737 |
| Molecular Weight: | |
| NCBI Full Name: | Programmed cell death protein 5 |
| NCBI Synonym Full Names: | programmed cell death 5 |
| NCBI Official Symbol: | PDCD5 |
| NCBI Official Synonym Symbols: | TFAR19 |
| NCBI Protein Information: | programmed cell death protein 5 |
| UniProt Protein Name: | Programmed cell death protein 5 |
| UniProt Synonym Protein Names: | TF-1 cell apoptosis-related protein 19; Protein TFAR19 |
| Protein Family: | Programmed cell death protein |
| UniProt Gene Name: | PDCD5 |
| UniProt Entry Name: | PDCD5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PDCD5 Antibody (CAB7298) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s. |
 | Immunofluorescence analysis of L929 cells using PDCD5 Rabbit pAb (CAB7298) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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