Anti-PD-1/CD279 Antibody (CAB20217)
- SKU:
- CAB20217
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG
- Synonyms:
- PDCD1
- Synonyms:
- CD279
- Synonyms:
- PD-1
- Synonyms:
- PD1
- Synonyms:
- SLEB2
- Synonyms:
- hPD-1
- Synonyms:
- hPD-l
- Synonyms:
- hSLE1
- Research Area:
- Immunology
Description
| Product Name: | PD-1/CD279 Mouse mAb |
| Product Code: | CAB20217 |
| Size: | 50uL, 100uL |
| Synonyms: | PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 |
| Applications: | IHC |
| Reactivity: | Human |
| Host Species: | Mouse |
| Immunogen: | Recombinant protein of human PD-1/CD279. |
| Applications: | IHC |
| Recommended Dilutions: | IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human PD-1/CD279. |
| Purification Method: | Affinity purification |
| Storage: | Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% thimerosal, 0.05% BSA, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5133 |
| Uniprot: | Q15116 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 31kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors. |
| NCBI Summary: | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15116 |
| NCBI GenInfo Identifier: | 145559515 |
| NCBI Gene ID: | 5133 |
| NCBI Accession: | Q15116.3 |
| UniProt Secondary Accession: | Q15116,Q02242, |
| UniProt Related Accession: | Q15116 |
| Molecular Weight: | |
| NCBI Full Name: | Programmed cell death protein 1 |
| NCBI Synonym Full Names: | programmed cell death 1 |
| NCBI Official Symbol: | PDCD1 |
| NCBI Official Synonym Symbols: | PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 |
| NCBI Protein Information: | programmed cell death protein 1 |
| UniProt Protein Name: | Programmed cell death protein 1 |
| UniProt Synonym Protein Names: | CD_antigen: CD279 |
| UniProt Gene Name: | PDCD1 |
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