Cell Biology Antibodies 14

Anti-PCYT1A Antibody (CAB16943)

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SKU:
CAB16943
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PCYT1A Antibody
Antibody SKU:CAB16943
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PCYT1A (NP_001299602.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, HepG2, Mouse testis, Mouse brain
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PCYT1A (NP_001299602.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDAQ CSAK VNAR KRRK EAPG PNGA TEED GVPS KVQR CAVG LRQP APFS DEIE VDFS KPYV RVTM EEAS RGTP CERP VRVY ADGI FDLF HSGH ARAL MQAK
Gene ID:5130
Uniprot:P49585
Cellular Location:
Calculated MW:
Observed MW:42kDa
Anti-PCYT1A Antibody (CAB16943)Western blot - PCYT1A Rabbit pAb (CAB16943)
Synonyms:PCYT1A, CCTA, CT, CTA, CTPCT, PCYT1, SMDCRD
Background:This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:PCYT1A: Controls phosphatidylcholine synthesis. Homodimer. By phosphorylation. Belongs to the cytidylyltransferase family.
UniProt Protein Details:

Protein type:Transferase; Lipid Metabolism - glycerophospholipid; EC 2.7.7.15

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: endoplasmic reticulum membrane; glycogen granule

Molecular Function:choline-phosphate cytidylyltransferase activity

Biological Process: CDP-choline pathway; phosphatidylcholine biosynthetic process

Disease: Spondylometaphyseal Dysplasia With Cone-rod Dystrophy

NCBI Summary:This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
UniProt Code:P49585
NCBI GenInfo Identifier:166214967
NCBI Gene ID:5130
NCBI Accession:P49585.2
UniProt Secondary Accession:P49585,Q86Y88, A9LYK9, D3DXB1,
UniProt Related Accession:P49585
Molecular Weight:41,731 Da
NCBI Full Name:Choline-phosphate cytidylyltransferase A
NCBI Synonym Full Names:phosphate cytidylyltransferase 1, choline, alpha
NCBI Official Symbol:PCYT1A  
NCBI Official Synonym Symbols:CT; CTA; CCTA; CTPCT; PCYT1; SMDCRD  
NCBI Protein Information:choline-phosphate cytidylyltransferase A
UniProt Protein Name:Choline-phosphate cytidylyltransferase A
UniProt Synonym Protein Names:CCT-alpha; CTP:phosphocholine cytidylyltransferase A; CCT A; CT A; Phosphorylcholine transferase A
Protein Family:Choline-phosphate cytidylyltransferase
UniProt Gene Name:PCYT1A  
UniProt Entry Name:PCY1A_HUMAN
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OverviewProduct Name:PCYT1A Rabbit mAbProduct Code:CAB5935Size:20uL, 50uL, 100uLSynonyms:CCTA, CT, CTA, CTPCT, PCYT1, SMDCRD