Cell Biology Antibodies 17
Anti-PCGF5 Antibody (CAB18511)
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- SKU:
- CAB18511
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PCGF5 Antibody |
| Antibody SKU: | CAB18511 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PCGF5. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human PCGF5. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 84333 |
| Uniprot: | Q86SE9 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | RNF159, PCGF5 |
| Background: |
| UniProt Protein Function: | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:26151332). Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (PubMed:26151332). Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. |
| UniProt Code: | Q86SE9 |
| NCBI GenInfo Identifier: | 375065846 |
| NCBI Gene ID: | 84333 |
| NCBI Accession: | NP_001243478.1 |
| UniProt Secondary Accession: | Q86SE9,Q6PK47, Q86TD0, B7Z892, D3DR33, |
| UniProt Related Accession: | Q86SE9 |
| Molecular Weight: | 5,779 Da |
| NCBI Full Name: | polycomb group RING finger protein 5 |
| NCBI Synonym Full Names: | polycomb group ring finger 5 |
| NCBI Official Symbol: | PCGF5 |
| NCBI Official Synonym Symbols: | RNF159 |
| NCBI Protein Information: | polycomb group RING finger protein 5 |
| UniProt Protein Name: | Polycomb group RING finger protein 5 |
| UniProt Synonym Protein Names: | RING finger protein 159 |
| Protein Family: | Polycomb group RING finger protein |
| UniProt Gene Name: | PCGF5 |
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