Cell Biology Antibodies 17

Anti-PCGF5 Antibody (CAB18511)

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SKU:
CAB18511

Description

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Antibody Name:Anti-PCGF5 Antibody
Antibody SKU:CAB18511
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human PCGF5.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant protein of human PCGF5.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:84333
Uniprot:Q86SE9
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:RNF159, PCGF5
Background:
UniProt Protein Function:Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:26151332). Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (PubMed:26151332). Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females.
UniProt Code:Q86SE9
NCBI GenInfo Identifier:375065846
NCBI Gene ID:84333
NCBI Accession:NP_001243478.1
UniProt Secondary Accession:Q86SE9,Q6PK47, Q86TD0, B7Z892, D3DR33,
UniProt Related Accession:Q86SE9
Molecular Weight:5,779 Da
NCBI Full Name:polycomb group RING finger protein 5
NCBI Synonym Full Names:polycomb group ring finger 5
NCBI Official Symbol:PCGF5  
NCBI Official Synonym Symbols:RNF159  
NCBI Protein Information:polycomb group RING finger protein 5
UniProt Protein Name:Polycomb group RING finger protein 5
UniProt Synonym Protein Names:RING finger protein 159
Protein Family:Polycomb group RING finger protein
UniProt Gene Name:PCGF5  
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Additional Information

Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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