Epigenetics & Nuclear Signaling Antibodies 4
Anti-PCGF3 Antibody (CAB7459)
(No reviews yet)
Write a Review
- SKU:
- CAB7459
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-PCGF3 Antibody |
| Antibody SKU: | CAB7459 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human PCGF3 (NP_006306.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse kidney, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human PCGF3 (NP_006306.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MLTR KIKL WDIN AHIT CRLC SGYL IDAT TVTE CLHT FCRS CLVK YLEE NNTC PTCR IVIH QSHP LQYI GHDR TMQD IVYK LVPG LQEA EMRK QREF YHKL GMEV PGDI KGET CSAK QHLD SHRN GETK ADDS SNKE AAEE KPEE DNDY HRSD EQVS ICLE CNSS KLRG LKRK WIRC SAQA TVLH LKKF IAKK LNLS SFNE LDIL CNEE ILGK DHTL KFVV VTRW RFKK APLL LHYR PKMD LL |
| Gene ID: | 10336 |
| Uniprot: | Q3KNV8 |
| Cellular Location: | Nucleus |
| Calculated MW: | 28kDa |
| Observed MW: | 28kDa |
| Synonyms: | PCGF3, DONG1, RNF3, RNF3A |
| Background: | The protein encoded by this gene contains a C3HC4 type RING finger, which is a motif known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. |
| UniProt Protein Function: | PCGF3: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: nucleoplasm; PcG protein complex; nucleus Molecular Function:protein binding; zinc ion binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| NCBI Summary: | The protein encoded by this gene contains a C3HC4 type RING finger, which is a motif known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q3KNV8 |
| NCBI GenInfo Identifier: | 121942537 |
| NCBI Gene ID: | 10336 |
| NCBI Accession: | Q3KNV8.1 |
| UniProt Secondary Accession: | Q3KNV8,O15262, D3DVN1, |
| UniProt Related Accession: | Q3KNV8 |
| Molecular Weight: | 28 kDa |
| NCBI Full Name: | Polycomb group RING finger protein 3 |
| NCBI Synonym Full Names: | polycomb group ring finger 3 |
| NCBI Official Symbol: | PCGF3 |
| NCBI Official Synonym Symbols: | RNF3; DONG1; RNF3A |
| NCBI Protein Information: | polycomb group RING finger protein 3; ring finger protein 3; RING finger protein 3A |
| UniProt Protein Name: | Polycomb group RING finger protein 3 |
| UniProt Synonym Protein Names: | RING finger protein 3A |
| Protein Family: | Polycomb group RING finger protein |
| UniProt Gene Name: | PCGF3 |
| UniProt Entry Name: | PCGF3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PCGF3 antibody (CAB7459) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Anti-MMUT Antibody (CAB9406)
OverviewAntibody Name:Anti-MMUT Antibody (CAB9406)Antibody SKU:CAB9406Antibody Size:50µL, 100µLApplication:Western blotting, Immunohistochemistry