Epigenetics & Nuclear Signaling Antibodies 2
Anti-PCF11 Antibody (CAB16533)
- SKU:
- CAB16533
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Antibody Name: | Anti-PCF11 Antibody |
Antibody SKU: | CAB16533 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1256-1555 of human PCF11 (NP_056969.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | LO2, Jurkat, HeLa, Mouse testis |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1256-1555 of human PCF11 (NP_056969.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | PKAY PDNH LSQV DVNE LFSK LLKT GILK LSQT DSAT TQVS EVTA QPPP EEEE DQNE DQDV PDLT NFTV EELK QRYD SVIN RLYT GIQC YSCG MRFT TSQT DVYA DHLD WHYR QNRT EKDV SRKV THRR WYYS LTDW IEFE EIAD LEER AKSQ FFEK VHEE VVLK TQEA AKEK EFQS VPAG PAGA VESC EICQ EQFE QYWD EEEE EWHL KNAI RVDG KIYH PSCY EDYQ NTSS FDCT PSPS KTPV ENPL NIML NIVK NELQ EPCD SPKV KEER IDTP PACT EESI ATPS EIKT ENDT VESV |
Gene ID: | 51585 |
Uniprot: | O94913 |
Cellular Location: | Nucleus |
Calculated MW: | 173kDa |
Observed MW: | 180kDa |
Synonyms: | PCF11 |
Background: | The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. |
UniProt Protein Function: | PCF11: Component of pre-mRNA cleavage complex II. |
UniProt Protein Details: | Protein type:RNA processing; RNA splicing Chromosomal Location of Human Ortholog: 11q13 Cellular Component: cytoplasm; mRNA cleavage factor complex; nucleoplasm Molecular Function:mRNA binding Biological Process: mRNA 3'-end processing; mRNA cleavage; mRNA polyadenylation; nuclear mRNA splicing, via spliceosome; termination of RNA polymerase II transcription |
UniProt Code: | O94913 |
NCBI GenInfo Identifier: | 33620745 |
NCBI Gene ID: | 51585 |
NCBI Accession: | NP_056969.2 |
UniProt Secondary Accession: | O94913,O43671, Q6P0X8, A6H8W7, |
UniProt Related Accession: | O94913 |
Molecular Weight: | 173,050 Da |
NCBI Full Name: | pre-mRNA cleavage complex 2 protein Pcf11 |
NCBI Synonym Full Names: | PCF11 cleavage and polyadenylation factor subunit |
NCBI Official Symbol: | PCF11 |
NCBI Protein Information: | pre-mRNA cleavage complex 2 protein Pcf11 |
UniProt Protein Name: | Pre-mRNA cleavage complex 2 protein Pcf11 |
UniProt Synonym Protein Names: | Pre-mRNA cleavage complex II protein Pcf11 |
Protein Family: | Protein |
UniProt Gene Name: | PCF11 |
UniProt Entry Name: | PCF11_HUMAN |
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