Cell Biology Antibodies 2
Anti-PCDH17 Antibody (CAB10512)
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- SKU:
- CAB10512
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PCDH17 Antibody |
| Antibody SKU: | CAB10512 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 610-710 of human PCDH17 (NP_001035519.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 610-710 of human PCDH17 (NP_001035519.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VRAL DSDF GESG RLTY EIVD GNDD HLFE IDPS SGEI RTLH PFWE DVTP VVEL VVKV TDHG KPTL SAVA KLII RSVS GSLP EGVP RVNG EQHH WDMS LPLI V |
| Gene ID: | 27253 |
| Uniprot: | O14917 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 96kDa/126kDa |
| Observed MW: | 150kDa |
| Synonyms: | PCDH17, PCDH68, PCH68 |
| Background: | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain. |
| UniProt Protein Function: | PCDH17: Potential calcium-dependent cell-adhesion protein. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 13q21.1 Cellular Component: integral to plasma membrane Molecular Function:protein binding Biological Process: cell adhesion; cell-cell signaling; synaptogenesis |
| NCBI Summary: | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14917 |
| NCBI GenInfo Identifier: | 118572683 |
| NCBI Gene ID: | 27253 |
| NCBI Accession: | O14917.2 |
| UniProt Secondary Accession: | O14917,Q5VVW9, Q5VVX0, A8K1R5, |
| UniProt Related Accession: | O14917 |
| Molecular Weight: | 126kDa |
| NCBI Full Name: | Protocadherin-17 |
| NCBI Synonym Full Names: | protocadherin 17 |
| NCBI Official Symbol: | PCDH17 |
| NCBI Official Synonym Symbols: | PCH68; PCDH68 |
| NCBI Protein Information: | protocadherin-17 |
| UniProt Protein Name: | Protocadherin-17 |
| UniProt Synonym Protein Names: | Protocadherin-68 |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDH17 |
 | Western blot analysis of extracts of 293T cells, using PCDH17 antibody (CAB10512) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. |
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