Cell Biology Antibodies 2

Anti-PCDH10 Antibody (CAB11632)

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SKU:
CAB11632
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PCDH10 Antibody
Antibody SKU:CAB11632
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 791-1040 of human PCDH10 (NP_116586.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SKOV3, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 791-1040 of human PCDH10 (NP_116586.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QSSN VPSN PAQV PIEE SGGF GSHH HNQN YCYQ VCLT PESA KTDL MFLK PCSP SRST DTEH NPCG AIVT GYTD QQPD IISN GSIL SNET KHQR AELS YLVD RPRR VNSS AFQE ADIV SSKD SGHG DSEQ GDSD HDAT NRAQ SAGM DLFS NCTE ECKA LGHS DRCW MPSF VPSD GRQA ADYR SNLH VPGM DSVP DTEV FETP EAQP GAER SFST FGKE KALH STLE RKEL DGLL TNTR APYK PPYL TRKR IC
Gene ID:57575
Uniprot:Q9P2E7
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:97kDa/112kDa
Observed MW:113kDa
Synonyms:PCDH10, OL-PCDH, PCDH19
Background:This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:PCDH10: Potential calcium-dependent cell-adhesion protein.
UniProt Protein Details:

Protein type:Calcium-binding; Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q28.3

Cellular Component: integral to plasma membrane

Biological Process: cell adhesion; cell-cell signaling; nervous system development

NCBI Summary:This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
UniProt Code:Q9P2E7
NCBI GenInfo Identifier:41017507
NCBI Gene ID:57575
NCBI Accession:Q9P2E7.2
UniProt Secondary Accession:Q9P2E7,Q4W5F6, Q96SF0,
UniProt Related Accession:Q9P2E7
Molecular Weight:113kDa
NCBI Full Name:Protocadherin-10
NCBI Synonym Full Names:protocadherin 10
NCBI Official Symbol:PCDH10  
NCBI Official Synonym Symbols:PCDH19; OL-PCDH  
NCBI Protein Information:protocadherin-10
UniProt Protein Name:Protocadherin-10
Protein Family:Protocadherin
UniProt Gene Name:PCDH10  
Anti-PCDH10 Antibody (CAB11632)Western blot analysis of extracts of various cell lines, using PCDH10 antibody (CAB11632) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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