Cell Biology Antibodies 1

Anti-PCDH10 Antibody (CAB10150)

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SKU:
CAB10150
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PCDH10 Antibody
Antibody SKU:CAB10150
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human PCDH10
Application:WB
Recommended Dilution:WB 1:200 - 1:1000
Reactivity:Human, Mouse, Rat
Positive Samples:SKOV3, Mouse brain, Rat brain
Immunogen:Recombinant protein of human PCDH10
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:57575
Uniprot:Q9P2E7
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:97kDa/112kDa
Observed MW:113kDa
Synonyms:PCDH10, OL-PCDH, PCDH19
Background:This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:PCDH10: Potential calcium-dependent cell-adhesion protein.
UniProt Protein Details:

Protein type:Calcium-binding; Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q28.3

Cellular Component: integral to plasma membrane

Biological Process: cell adhesion; cell-cell signaling; nervous system development

NCBI Summary:This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
UniProt Code:Q9P2E7
NCBI GenInfo Identifier:41017507
NCBI Gene ID:57575
NCBI Accession:Q9P2E7.2
UniProt Secondary Accession:Q9P2E7,Q4W5F6, Q96SF0,
UniProt Related Accession:Q9P2E7
Molecular Weight:113kDa
NCBI Full Name:Protocadherin-10
NCBI Synonym Full Names:protocadherin 10
NCBI Official Symbol:PCDH10  
NCBI Official Synonym Symbols:PCDH19; OL-PCDH  
NCBI Protein Information:protocadherin-10
UniProt Protein Name:Protocadherin-10
Protein Family:Protocadherin
UniProt Gene Name:PCDH10  
Anti-PCDH10 Antibody (CAB10150)Western blot analysis of extracts of various cell lines, using PCDH10 antibody (CAB10150) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 60s.
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