Description
Product Name: | PBRM1 Rabbit mAb |
Product Code: | CAB0334 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | BAF180, PB1 |
Applications: | WB, IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human PBRM1 |
Applications: | WB, IHC |
Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HeLa, NIH/3T3, Jurkat, Rat brain |
Immunogen: | A synthesized peptide derived from human PBRM1 |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 55193 |
Uniprot: | Q86U86 |
Calculated MW: | 193kDa |
Observed MW: | 220kDa |
UniProt Protein Function: | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. |
NCBI Summary: | This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012] |
UniProt Code: | Q86U86 |
NCBI GenInfo Identifier: | 73921624 |
NCBI Gene ID: | 55193 |
NCBI Accession: | Q86U86.1 |
UniProt Secondary Accession: | Q86U86,Q1RMD1, Q1RMD2, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5 Q9H301, Q9H314, A1L381, A1L382, A4FUJ7, |
UniProt Related Accession: | Q86U86 |
Molecular Weight: | 184,043 Da |
NCBI Full Name: | Protein polybromo-1 |
NCBI Synonym Full Names: | polybromo 1 |
NCBI Official Symbol: | PBRM1 |
NCBI Official Synonym Symbols: | PB1; BAF180 |
NCBI Protein Information: | protein polybromo-1 |
UniProt Protein Name: | Protein polybromo-1 |
UniProt Synonym Protein Names: | BRG1-associated factor 180; BAF180; Polybromo-1D |
Protein Family: | Protein polybromo |
UniProt Gene Name: | PBRM1 |
UniProt Entry Name: | PB1_HUMAN |