Anti-PBRM1 Antibody (CAB0334)
- SKU:
- CAB0334
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BAF180
- Synonyms:
- PB1
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | PBRM1 Rabbit mAb |
| Product Code: | CAB0334 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | BAF180, PB1 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PBRM1 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, NIH/3T3, Jurkat, Rat brain |
| Immunogen: | A synthesized peptide derived from human PBRM1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55193 |
| Uniprot: | Q86U86 |
| Calculated MW: | 193kDa |
| Observed MW: | 220kDa |
| UniProt Protein Function: | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. |
| NCBI Summary: | This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q86U86 |
| NCBI GenInfo Identifier: | 73921624 |
| NCBI Gene ID: | 55193 |
| NCBI Accession: | Q86U86.1 |
| UniProt Secondary Accession: | Q86U86,Q1RMD1, Q1RMD2, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5 Q9H301, Q9H314, A1L381, A1L382, A4FUJ7, |
| UniProt Related Accession: | Q86U86 |
| Molecular Weight: | 184,043 Da |
| NCBI Full Name: | Protein polybromo-1 |
| NCBI Synonym Full Names: | polybromo 1 |
| NCBI Official Symbol: | PBRM1 |
| NCBI Official Synonym Symbols: | PB1; BAF180 |
| NCBI Protein Information: | protein polybromo-1 |
| UniProt Protein Name: | Protein polybromo-1 |
| UniProt Synonym Protein Names: | BRG1-associated factor 180; BAF180; Polybromo-1D |
| Protein Family: | Protein polybromo |
| UniProt Gene Name: | PBRM1 |
| UniProt Entry Name: | PB1_HUMAN |
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