Cell Biology Antibodies 3

Anti-PATL1 Antibody (CAB13170)

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SKU:
CAB13170
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PATL1 Antibody
Antibody SKU:CAB13170
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 535-640 of human PATL1 (NP_689929.2).
Application:WB
Recommended Dilution:WB 1:1000 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse kidney, Mouse brain, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 535-640 of human PATL1 (NP_689929.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DVED YERR YLLS LEEE RPAL MDDR KHKI CSMY DNLR GKLP GQER PSDD HFVQ IMCI RKGK RMVA RILP FLST EQAA DILM TTAR NLPF LIKK DAQD EVLP CLLS PF
Gene ID:219988
Uniprot:Q86TB9
Cellular Location:Cytoplasm, Nucleus, Nucleus speckle, P-body, PML body
Calculated MW:12kDa/70kDa/79kDa/86kDa
Observed MW:87kDa
Synonyms:PATL1, Pat1b, hPat1b
Background:
UniProt Protein Function:RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
UniProt Code:Q86TB9
NCBI GenInfo Identifier:182705251
NCBI Gene ID:219988
NCBI Accession:Q86TB9.2
UniProt Secondary Accession:Q86TB9,Q2TA86, Q6P166, Q8N9M6, Q8NI63, B3KXT9,
UniProt Related Accession:Q86TB9
Molecular Weight:79,908 Da
NCBI Full Name:Protein PAT1 homolog 1
NCBI Synonym Full Names:PAT1 homolog 1, processing body mRNA decay factor
NCBI Official Symbol:PATL1  
NCBI Official Synonym Symbols:Pat1b; hPat1b  
NCBI Protein Information:protein PAT1 homolog 1
UniProt Protein Name:Protein PAT1 homolog 1
UniProt Synonym Protein Names:PAT1-like protein 1; Protein PAT1 homolog b; Pat1b; hPat1b
Protein Family:Patellin
UniProt Gene Name:PATL1  
UniProt Entry Name:PATL1_HUMAN
Anti-PATL1 Antibody (CAB13170)Western blot analysis of extracts of various cell lines, using PATL1 antibody (CAB13170) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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