Cell Biology Antibodies 3
Anti-PATL1 Antibody (CAB13170)
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- SKU:
- CAB13170
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-PATL1 Antibody |
| Antibody SKU: | CAB13170 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 535-640 of human PATL1 (NP_689929.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse kidney, Mouse brain, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 535-640 of human PATL1 (NP_689929.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DVED YERR YLLS LEEE RPAL MDDR KHKI CSMY DNLR GKLP GQER PSDD HFVQ IMCI RKGK RMVA RILP FLST EQAA DILM TTAR NLPF LIKK DAQD EVLP CLLS PF |
| Gene ID: | 219988 |
| Uniprot: | Q86TB9 |
| Cellular Location: | Cytoplasm, Nucleus, Nucleus speckle, P-body, PML body |
| Calculated MW: | 12kDa/70kDa/79kDa/86kDa |
| Observed MW: | 87kDa |
| Synonyms: | PATL1, Pat1b, hPat1b |
| Background: |
| UniProt Protein Function: | RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV). |
| UniProt Code: | Q86TB9 |
| NCBI GenInfo Identifier: | 182705251 |
| NCBI Gene ID: | 219988 |
| NCBI Accession: | Q86TB9.2 |
| UniProt Secondary Accession: | Q86TB9,Q2TA86, Q6P166, Q8N9M6, Q8NI63, B3KXT9, |
| UniProt Related Accession: | Q86TB9 |
| Molecular Weight: | 79,908 Da |
| NCBI Full Name: | Protein PAT1 homolog 1 |
| NCBI Synonym Full Names: | PAT1 homolog 1, processing body mRNA decay factor |
| NCBI Official Symbol: | PATL1 |
| NCBI Official Synonym Symbols: | Pat1b; hPat1b |
| NCBI Protein Information: | protein PAT1 homolog 1 |
| UniProt Protein Name: | Protein PAT1 homolog 1 |
| UniProt Synonym Protein Names: | PAT1-like protein 1; Protein PAT1 homolog b; Pat1b; hPat1b |
| Protein Family: | Patellin |
| UniProt Gene Name: | PATL1 |
| UniProt Entry Name: | PATL1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PATL1 antibody (CAB13170) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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