Cell Cycle Antibodies 1
Anti-PARD6B Antibody (CAB5060)
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- SKU:
- CAB5060
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PARD6B
- Synonyms:
- PAR6B
- Research Area:
- Cell Cycle
Description
| Product Name: | PARD6B Rabbit pAb |
| Product Code: | CAB5060 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | PARD6B, PAR6B |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:1000 - 1:4000 |
| Reactivity: | Human |
| Positive Samples: | SH-SY5Y, MCF7, HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NNVV RNSR TSGS SGQS TDNS LLGY PQQI EPSF EPED EDSE EDDI IIED NGVP QQIP KAVP NTES LESL TQIE LSFE SGQN GFIP SNEV SLAA IASS SNTE FETH APDQ KLLE EDGT IITL |
| Gene ID: | 84612 |
| Uniprot: | Q9BYG5 |
| Cellular Location: | Cell junction, Cell membrane, Cytoplasm, tight junction |
| Calculated MW: | 12kDa/41kDa |
| Observed MW: | 41kDa |
| UniProt Protein Function: | PARD6B: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Belongs to the PAR6 family. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 20q13.13 Cellular Component: protein complex; tight junction; apical part of cell; cytoplasm; plasma membrane; cell cortex; nucleus; cytosol Molecular Function:protein binding Biological Process: intercellular junction assembly; intercellular junction assembly and maintenance; axonogenesis; cell division; establishment and/or maintenance of cell polarity; protein complex assembly; cell cycle; regulation of cell migration |
| NCBI Summary: | This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BYG5 |
| NCBI GenInfo Identifier: | 30913176 |
| NCBI Gene ID: | 84612 |
| NCBI Accession: | Q9BYG5.1 |
| UniProt Secondary Accession: | Q9BYG5,Q9Y510, A2A2A7, |
| UniProt Related Accession: | Q9BYG5 |
| Molecular Weight: | 372 |
| NCBI Full Name: | Partitioning defective 6 homolog beta |
| NCBI Synonym Full Names: | par-6 family cell polarity regulator beta |
| NCBI Official Symbol: | PARD6B |
| NCBI Official Synonym Symbols: | PAR6B |
| NCBI Protein Information: | partitioning defective 6 homolog beta; PAR-6 beta; par-6 partitioning defective 6 homolog beta |
| UniProt Protein Name: | Partitioning defective 6 homolog beta |
| Protein Family: | Partitioning defective |
| UniProt Gene Name: | PARD6B |
| UniProt Entry Name: | PAR6B_HUMAN |
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