Cell Biology Antibodies 18
Anti-PALM Antibody (CAB18371)
- SKU:
- CAB18371
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-PALM Antibody |
Antibody SKU: | CAB18371 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human PALM. |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse |
Positive Samples: |
Immunogen: | Recombinant protein of human PALM. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 5064 |
Uniprot: | O75781 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | Refer to figures |
Synonyms: | PALM |
Background: |
UniProt Protein Function: | paralemmin: Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. Belongs to the paralemmin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleoplasm; filopodium membrane; intracellular membrane-bound organelle; apicolateral plasma membrane; axon; basolateral plasma membrane; integral to plasma membrane; cytoplasmic membrane-bound vesicle; plasma membrane; nucleus Molecular Function:protein binding; D3 dopamine receptor binding Biological Process: positive regulation of filopodium formation; regulation of cell shape; synapse maturation; negative regulation of dopamine receptor signaling pathway; negative regulation of adenylate cyclase activity; cytoskeleton organization and biogenesis; cell motility |
UniProt Code: | O75781 |
NCBI GenInfo Identifier: | 4456613 |
NCBI Gene ID: | |
NCBI Accession: | CAB37400.1 |
UniProt Secondary Accession: | O75781,O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3 |
Molecular Weight: | 37,157 Da |
NCBI Full Name: | paralemmin |
UniProt Protein Name: | Paralemmin-1 |
UniProt Synonym Protein Names: | Paralemmin |
Protein Family: | Paralemmin |
UniProt Gene Name: | PALM |
UniProt Entry Name: | PALM_HUMAN |