Cell Biology Antibodies 18

Anti-PALM Antibody (CAB18371)

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SKU:
CAB18371
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PALM Antibody
Antibody SKU:CAB18371
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human PALM.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant protein of human PALM.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5064
Uniprot:O75781
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:PALM
Background:
UniProt Protein Function:paralemmin: Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. Belongs to the paralemmin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; filopodium membrane; intracellular membrane-bound organelle; apicolateral plasma membrane; axon; basolateral plasma membrane; integral to plasma membrane; cytoplasmic membrane-bound vesicle; plasma membrane; nucleus

Molecular Function:protein binding; D3 dopamine receptor binding

Biological Process: positive regulation of filopodium formation; regulation of cell shape; synapse maturation; negative regulation of dopamine receptor signaling pathway; negative regulation of adenylate cyclase activity; cytoskeleton organization and biogenesis; cell motility

UniProt Code:O75781
NCBI GenInfo Identifier:4456613
NCBI Gene ID:
NCBI Accession:CAB37400.1
UniProt Secondary Accession:O75781,O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3
Molecular Weight:37,157 Da
NCBI Full Name:paralemmin
UniProt Protein Name:Paralemmin-1
UniProt Synonym Protein Names:Paralemmin
Protein Family:Paralemmin
UniProt Gene Name:PALM  
UniProt Entry Name:PALM_HUMAN
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