Cell Biology Antibodies 12

Anti-PACSIN3 Antibody (CAB8647)

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SKU:
CAB8647
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PACSIN3 Antibody
Antibody SKU:CAB8647
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 175-424 of human PACSIN3 (NP_057307.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, MCF7, HeLa, Jurkat, Mouse heart, Mouse liver, Mouse lung, Rat liver, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 175-424 of human PACSIN3 (NP_057307.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KADS AVSQ EQLR KLQE RVER CAKE AEKT KAQY EQTL AELH RYTP RYME DMEQ AFET CQAA ERQR LLFF KDML LTLH QHLD LSSS EKFH ELHR DLHQ GIEA ASDE EDLR WWRS THGP GMAM NWPQ FEEW SLDT QRTI SRKE KGGR SPDE VTLT SIVP TRDG TAPP PQSP GSPG TGQD EEWS DEES PRKA ATGV RVRA LYDY AGQE ADEL SFRA GEEL LKMS EEDE QGWC QGQL QSGR IGLY PANY VECV GA
Gene ID:29763
Uniprot:Q9UKS6
Cellular Location:Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein
Calculated MW:48kDa
Observed MW:48kDa
Synonyms:PACSIN3, SDPIII
Background:This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:PACSIN3: May play a role in vesicle formation and transport. Belongs to the PACSIN family.
UniProt Protein Details:

Protein type:Adaptor/scaffold; Vesicle

Chromosomal Location of Human Ortholog: 11p12-p11.12

Cellular Component: cytoplasm; endosome; nucleoplasm; plasma membrane

Molecular Function:calcium channel inhibitor activity; cytoskeletal protein binding; lipid binding; protein binding

Biological Process: negative regulation of calcium ion transport; negative regulation of endocytosis; positive regulation of membrane protein ectodomain proteolysis; regulation of endocytosis

NCBI Summary:This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:Q9UKS6
NCBI GenInfo Identifier:22256967
NCBI Gene ID:29763
NCBI Accession:Q9UKS6.2
UniProt Secondary Accession:Q9UKS6,Q9H331, Q9NWV9, A6NH84,
UniProt Related Accession:Q9UKS6
Molecular Weight:48,487 Da
NCBI Full Name:Protein kinase C and casein kinase substrate in neurons protein 3
NCBI Synonym Full Names:protein kinase C and casein kinase substrate in neurons 3
NCBI Official Symbol:PACSIN3  
NCBI Official Synonym Symbols:SDPIII  
NCBI Protein Information:protein kinase C and casein kinase substrate in neurons protein 3
UniProt Protein Name:Protein kinase C and casein kinase substrate in neurons protein 3
UniProt Synonym Protein Names:SH3 domain-containing protein 6511
Protein Family:Protein kinase C and casein kinase II substrate protein
UniProt Gene Name:PACSIN3  
UniProt Entry Name:PACN3_HUMAN
Anti-PACSIN3 Polyclonal Antibody (CAB8647)Western blot analysis of extracts of various cell lines, using PACSIN3 antibody (CAB8647) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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