Name: Anti-PACSIN2 Antibody (CAB19941)[KO Validated]
Brand: KO Validated Antibodies 2
SKU: CAB19941
Availability: OutOfStock

Antibody Name:	Anti-PACSIN2 Antibody [KO Validated]
Antibody SKU:	CAB19941
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant protein of human PACSIN2.

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	HeLa

Immunogen:	Recombinant protein of human PACSIN2.
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	11252
Uniprot:	Q9UNF0
Cellular Location:	Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome, Membrane, Peripheral membrane protein, Recycling endosome membrane, caveola, cytoskeleton, ruffle membrane
Calculated MW:	51kDa/55kDa
Observed MW:	62KDa

Anti-PACSIN2 Antibody [KO Validated] (CAB19941)

Western blot analysis of extracts from normal (control) and PACSIN2 knockout (KO) HeLa cells, using PACSIN2 antibody (CAB19941) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.

Synonyms:	PACSIN2, SDPII
Background:	This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants.

UniProt Protein Function:	PACSIN2: May play a role in vesicle formation and transport. Belongs to the PACSIN family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 22q13.2-q13.33 Cellular Component: caveola; cytoplasm; extrinsic to membrane; focal adhesion; intracellular membrane-bound organelle; nucleoplasm; recycling endosome membrane Molecular Function:identical protein binding; protein binding; transporter activity Biological Process: cell projection morphogenesis; regulation of endocytosis
NCBI Summary:	This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:	Q9UNF0
NCBI GenInfo Identifier:	22256968
NCBI Gene ID:	11252
NCBI Accession:	Q9UNF0.2
UniProt Secondary Accession:	Q9UNF0,O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2,
UniProt Related Accession:	Q9UNF0
Molecular Weight:	51,353 Da
NCBI Full Name:	Protein kinase C and casein kinase substrate in neurons protein 2
NCBI Synonym Full Names:	protein kinase C and casein kinase substrate in neurons 2
NCBI Official Symbol:	PACSIN2
NCBI Official Synonym Symbols:	SDPII
NCBI Protein Information:	protein kinase C and casein kinase substrate in neurons protein 2
UniProt Protein Name:	Protein kinase C and casein kinase substrate in neurons protein 2
UniProt Synonym Protein Names:	Syndapin-2; Syndapin-II
Protein Family:	Protein kinase C and casein kinase substrate in neurons protein
UniProt Gene Name:	PACSIN2
UniProt Entry Name:	PACN2_HUMAN