Metabolism Antibodies 3

Anti-OXSM Antibody (CAB15852)

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SKU:
CAB15852
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-OXSM Antibody
Antibody SKU:CAB15852
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-459 of human OXSM (NP_060367.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, 293T, HeLa, Mouse heart, Mouse kidney, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-459 of human OXSM (NP_060367.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EYKS IPCS VAAY VPRG SDEG QFNE QNFV SKSD IKSM SSPT IMAI GAAE LAMK DSGW HPQS EADQ VATG VAIG MGMI PLEV VSET ALNF QTKG YNKV SPFF VPKI LVNM AAGQ VSIR YKLK GPNH AVST ACTT GAHA VGDS FRFI AHGD ADVM VAGG TDSC ISPL SLAG FSRA RALS TNSD PKLA CRPF HPKR DGFV MGEG AAVL VLEE YEHA VQRR ARIY AEVL GYGL SGDA GHIT APDP EGEG ALRC MAAA LKDA GVQP EEIS YINA HATS TPLG DAAE NKAI KHLF KDHA YALA VSST KGAT GHLL GAAG AVEA AFTT LACY YQKL PPTL NLDC SEPE FDLN YVPL KAQE WKTE KRFI GLTN SFGF GGTN ATLC IAGL
Gene ID:54995
Uniprot:Q9NWU1
Cellular Location:Mitochondrion
Calculated MW:40kDa/48kDa
Observed MW:49kDa
Synonyms:OXSM, CEM1, FASN2D, KASI, KS
Background:This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.
UniProt Protein Function:OXSM: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the beta-ketoacyl-ACP synthases family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transferase; EC 2.3.1.41; Lipid Metabolism - fatty acid biosynthesis; Mitochondrial

Chromosomal Location of Human Ortholog: 3p24.2

Cellular Component: mitochondrion; cytoplasm

Molecular Function:3-oxoacyl-[acyl-carrier-protein] synthase activity

Biological Process: medium-chain fatty acid biosynthetic process; acyl-CoA metabolic process; short-chain fatty acid biosynthetic process

NCBI Summary:This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]
UniProt Code:Q9NWU1
NCBI GenInfo Identifier:8923559
NCBI Gene ID:54995
NCBI Accession:NP_060367.1
UniProt Related Accession:Q9NWU1
Molecular Weight:49kDa
NCBI Full Name:3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform 1
NCBI Synonym Full Names:3-oxoacyl-ACP synthase, mitochondrial
NCBI Official Symbol:OXSM  
NCBI Official Synonym Symbols:KS; CEM1; KASI; FASN2D  
NCBI Protein Information:3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
UniProt Protein Name:3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
UniProt Synonym Protein Names:Beta-ketoacyl-ACP synthase
Protein Family:3-oxoacyl-[acyl-carrier-protein] synthase
UniProt Gene Name:OXSM  
UniProt Entry Name:OXSM_HUMAN
Anti-OXSM Antibody (CAB15852)Western blot analysis of extracts of various cell lines, using OXSM antibody (CAB15852) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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