Description
| Product Name: | OTULIN Rabbit pAb |
| Product Code: | CAB20489 |
| Size: | 50uL, 100uL |
| Synonyms: | GUM, AIPDS, FAM105B |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human OTULIN. |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, Rat liver |
| Immunogen: | Recombinant protein of human OTULIN. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 90268 |
| Uniprot: | Q96BN8 |
| Calculated MW: | 40kDa |
| Observed MW: | 45KDa |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016] |
| UniProt Code: | Q96BN8 |
| NCBI GenInfo Identifier: | 115334675 |
| NCBI Gene ID: | 90268 |
| NCBI Accession: | NP_612357 |
| UniProt Secondary Accession: | Q96BN8 |
| UniProt Related Accession: | Q96BN8 |
| Molecular Weight: | 38kDa |
| NCBI Full Name: | ubiquitin thioesterase otulin |
| NCBI Synonym Full Names: | OTU deubiquitinase with linear linkage specificity |
| NCBI Official Symbol: | OTULIN |
| NCBI Official Synonym Symbols: | GUM; AIPDS; FAM105B |
| NCBI Protein Information: | ubiquitin thioesterase otulin |
| UniProt Protein Name: | Ubiquitin thioesterase otulin |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme otulin; OTU domain-containing deubiquitinase with linear linkage specificity; Ubiquitin thioesterase Gumby |
| Protein Family: | Ubiquitin thioesterase otulin |
| UniProt Gene Name: | OTULIN |
| UniProt Entry Name: | OTUL_HUMAN |