Description
Product Name: | OTULIN Rabbit pAb |
Product Code: | CAB20489 |
Size: | 50uL, 100uL |
Synonyms: | GUM, AIPDS, FAM105B |
Applications: | WB, IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human OTULIN. |
Applications: | WB, IF |
Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | MCF7, Rat liver |
Immunogen: | Recombinant protein of human OTULIN. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 90268 |
Uniprot: | Q96BN8 |
Calculated MW: | 40kDa |
Observed MW: | 45KDa |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016] |
UniProt Code: | Q96BN8 |
NCBI GenInfo Identifier: | 115334675 |
NCBI Gene ID: | 90268 |
NCBI Accession: | NP_612357 |
UniProt Secondary Accession: | Q96BN8 |
UniProt Related Accession: | Q96BN8 |
Molecular Weight: | 38kDa |
NCBI Full Name: | ubiquitin thioesterase otulin |
NCBI Synonym Full Names: | OTU deubiquitinase with linear linkage specificity |
NCBI Official Symbol: | OTULIN |
NCBI Official Synonym Symbols: | GUM; AIPDS; FAM105B |
NCBI Protein Information: | ubiquitin thioesterase otulin |
UniProt Protein Name: | Ubiquitin thioesterase otulin |
UniProt Synonym Protein Names: | Deubiquitinating enzyme otulin; OTU domain-containing deubiquitinase with linear linkage specificity; Ubiquitin thioesterase Gumby |
Protein Family: | Ubiquitin thioesterase otulin |
UniProt Gene Name: | OTULIN |
UniProt Entry Name: | OTUL_HUMAN |