Immunology Antibodies 2

Anti-OTUD7B Antibody (CAB17329)

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SKU:
CAB17329
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-OTUD7B Antibody
Antibody SKU:CAB17329
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 530-700 of human OTUD7B (NP_064590.2).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:mouse liver, mouse kidney, mouse brain, rat liver, rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 530-700 of human OTUD7B (NP_064590.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SKPG GVGT GLGG SSGT ETLE KKKK NSLK SWKG GKEE AAGD GPVS EKPP AESV GNGG SKYS QEVM QSLS ILRT AMQG EGKF IFVG TLKM GHRH QYQE EMIQ RYLS DAEE RFLA EQKQ KEAE RKIM NGGI GGGP PPAK KPEP DARE EQPT GPPA ESRA MAFS TGYP GDFT IPR
Gene ID:56957
Uniprot:Q6GQQ9
Cellular Location:Cytoplasm, Nucleus
Calculated MW:88kDa/92kDa
Observed MW:95Da
Synonyms:OTUD7B, CEZANNE, ZA20D1
Background:
UniProt Protein Function:Cezanne: cellular zinc finger anti-NF-kappaB, a negative regulator of NF-kappaB. A novel deubiquitinating enzyme that belongs to the ovarian tumor protein (OTU) superfamily.
UniProt Protein Details:

Protein type:EC 3.4.19.12; Ubiquitin conjugating system; Protease

Chromosomal Location of Human Ortholog: 1q21.2

Cellular Component: cytoplasm; nucleus

Molecular Function:protein binding; DNA binding; zinc ion binding; ubiquitin-specific protease activity; cysteine-type peptidase activity

Biological Process: mucosal immune response; negative regulation of interleukin-8 production; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of transcription from RNA polymerase II promoter; proteolysis

UniProt Code:Q6GQQ9
NCBI GenInfo Identifier:51701318
NCBI Gene ID:56957
NCBI Accession:Q6GQQ9.1
UniProt Related Accession:Q6GQQ9
Molecular Weight:
NCBI Full Name:OTU domain-containing protein 7B
NCBI Synonym Full Names:OTU deubiquitinase 7B
NCBI Official Symbol:OTUD7B  
NCBI Official Synonym Symbols:ZA20D1; CEZANNE  
NCBI Protein Information:OTU domain-containing protein 7B
UniProt Protein Name:OTU domain-containing protein 7B
UniProt Synonym Protein Names:Cellular zinc finger anti-NF-kappa-B protein; Zinc finger A20 domain-containing protein 1; Zinc finger protein Cezanne
UniProt Gene Name:OTUD7B  
UniProt Entry Name:OTU7B_HUMAN
Anti-OTUD7B Antibody (CAB17329)Western blot analysis of extracts of various cell lines, using OTUD7B antibody (CAB17329) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-OTUD7B Antibody (CAB17329)Immunohistochemistry of paraffin-embedded Human colon using OTUD7B Rabbit pAb (CAB17329) at dilution of 1:100 (40x lens).
Anti-OTUD7B Antibody (CAB17329)Immunofluorescence analysis of L929 cells using OTUD7B antibody (CAB17329) at dilution of 1:100. Blue: DAPI for nuclear staining.
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