Anti-OTUD5 Antibody (CAB20516)
- SKU:
- CAB20516
Description
| Product Name: | OTUD5 Rabbit pAb |
| Product Code: | CAB20516 |
| Size: | 50uL, 100uL |
| Synonyms: | DUBA, MCAND |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55593 |
| Uniprot: | Q96G74 |
| Calculated MW: | 60kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | OTUD5: a protein of unknown function. Contains a OTU-like cysteine protease domain. Protein type: Ubiquitin-specific protease; Protease; EC 3.4.19.12 Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytosol Molecular Function: ubiquitin-specific protease activity Biological Process: innate immune response; response to lipopolysaccharide; proteolysis; negative regulation of interferon type I production |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q96G74 |
| NCBI GenInfo Identifier: | 209977019 |
| NCBI Gene ID: | 55593 |
| NCBI Accession: | NP_001129629.1 |
| UniProt Secondary Accession: | Q96G74,Q4KMN9, Q8N6T5, Q9H650, Q9H9U0, Q9NT65, B4DGG7 G5E9D7 |
| UniProt Related Accession: | Q96G74 |
| Molecular Weight: | |
| NCBI Full Name: | OTU domain-containing protein 5 isoform b |
| NCBI Synonym Full Names: | OTU deubiquitinase 5 |
| NCBI Official Symbol: | OTUD5 |
| NCBI Official Synonym Symbols: | DUBA |
| NCBI Protein Information: | OTU domain-containing protein 5; OTU domain containing 5; deubiquinating enzyme A; deubiquitinating enzyme A |
| UniProt Protein Name: | OTU domain-containing protein 5 |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme A; DUBA |
| Protein Family: | |
| UniProt Gene Name: | OTUD5 |
| UniProt Entry Name: | OTUD5_HUMAN |
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Polyclonal Antibody |
Reactivity: |
Human |
Host Species: |
Rabbit |
Isotype: |
IgG |
Synonyms: |
DUBA |
Synonyms: |
MCAND |
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