Cell Biology Antibodies 2

Anti-OSTF1 Antibody (CAB12169)

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SKU:
CAB12169
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-OSTF1 Antibody
Antibody SKU:CAB12169
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 15-214 of human OSTF1 (NP_036515.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, B cells, HeLa, HepG2, Mouse brain, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 15-214 of human OSTF1 (NP_036515.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KVFR ALYT FEPR TPDE LYFE EGDI IYIT DMSD TNWW KGTS KGRT GLIP SNYV AEQA ESID NPLH EAAK RGNL SWLR ECLD NRVG VNGL DKAG STAL YWAC HGGH KDIV EMLF TQPN IELN QQNK LGDT ALHA AAWK GYAD IVQL LLAK GART DLRN IEKK LAFD MATN AACA SLLK KKQG TDAV RTLS NAED YLDD EDSD
Gene ID:26578
Uniprot:Q92882
Cellular Location:Cytoplasm
Calculated MW:23kDa
Observed MW:26kDa
Synonyms:OSTF1, OSF, SH3P2, bA235O14.1
Background:
UniProt Protein Function:OSTF1: Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
UniProt Protein Details:

Protein type:Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: extracellular region; intracellular

Molecular Function:protein binding

Biological Process: neutrophil degranulation; ossification; signal transduction

NCBI Summary:Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008]
UniProt Code:Q92882
NCBI GenInfo Identifier:108885279
NCBI Gene ID:26578
NCBI Accession:Q92882.2
UniProt Secondary Accession:Q92882,Q5W126, Q96IJ4,
UniProt Related Accession:Q92882
Molecular Weight:24kDa
NCBI Full Name:Osteoclast-stimulating factor 1
NCBI Synonym Full Names:osteoclast stimulating factor 1
NCBI Official Symbol:OSTF1  
NCBI Official Synonym Symbols:OSF; SH3P2; bA235O14.1  
NCBI Protein Information:osteoclast-stimulating factor 1
UniProt Protein Name:Osteoclast-stimulating factor 1
Protein Family:Osteoclast-stimulating factor
UniProt Gene Name:OSTF1  
Anti-OSTF1 Antibody (CAB12169)Western blot analysis of extracts of various cell lines, using OSTF1 antibody (CAB12169) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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